Therapeutics of Boswellic Acid Derivatives as Anti-cancer Agent - Qurishi, Yasrib
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This book revealed that acyl derivatives of ¿-boswellic acid provide evidence about the apoptotic nature and development of these novel compounds for anticancer therapeutics. Our findings may open up a new perspective in the construction of novel anticancer agents that will facilitate the development of these agents capable of inducing apoptosis in cancer cells, particularly the leukemia. Thus, the work included in this book yielded substantial information to the growing knowledge of the cellular effects exerted by BAs on apoptosis with particular focus on leukemia cell types. Importantly,…mehr

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Produktbeschreibung
This book revealed that acyl derivatives of ¿-boswellic acid provide evidence about the apoptotic nature and development of these novel compounds for anticancer therapeutics. Our findings may open up a new perspective in the construction of novel anticancer agents that will facilitate the development of these agents capable of inducing apoptosis in cancer cells, particularly the leukemia. Thus, the work included in this book yielded substantial information to the growing knowledge of the cellular effects exerted by BAs on apoptosis with particular focus on leukemia cell types. Importantly, description of cellular effects, target identification for BAs was an intended aim of the investigations. In the course of this book, NF-kB and PARP were found as the targets for POBA and BOBA (derivatives of ¿-BA), but certainly specific upstream target(s) important for cell proliferation signaling needs to be identified. Broad scientific interest for BAs and B. spec effects has grown within the recent years, as reflected by the increasing number of scientific studies, so exciting novel insights into molecular, cellular and clinical BA effects are likely to come up in the future.
Autorenporträt
Currently she is Post Doctoral Fellow at IISc, Bangalore. She did M.Sc from University of Kashmir in 2008 and completed her project work from AIIMS, New Delhi. She was awarded M.phil in 2010 based on research work conducted at CSIR-IIIM Jammu. During her Ph.D, she was awarded CSIR-SRF and was also the reviewer of international journals of repute.