Jason Armstrong, Ovidiu Pascu (Consultant Emergency Physician and Clinical Toxicolog

The Toxicology Handbook

• Broschiertes Buch

Produktbeschreibung

Now in its fourth edition, the Toxicology Handbook is Australia's leading reference guide for quick and evidence-informed decision making on treatment of the acutely poisoned patient. The book has been streamlined and fully updated to provide a comprehensive yet concise guide for all medical practitioners and health-care professionals who deal with poisonings. It contains quickly accessible information on poisons, toxins, antidotes, envenomings and antivenoms, and uses a structured and rigorous risk assessment-based approach to guide appropriate treatment decisions. Written by leading Australian specialists in toxicology and informed by the latest clinical research, this is a must-have addition to all emergency departments and poison information centres. * Concisely written - helps the student, trainee, and clinician to find information quickly and easily * A simple, easily remembered and elegant framework (R RSI DEAD) forming the basis of care for all toxicology patients * Fully revised content, streamlined to be more user-friendly * Evidence based and up to date - supports appropriate decision making * Helps resolve common treatment dilemmas, including for digoxin and lithium poisoning, corrosive ingestions and management of envenomings * Written and edited by experts in the field of toxicology * An eBook included in all print purchases * Expanded information on agents that are seen with increasing frequency in poisoned patients, including lamotrigine and pregabalin * Updated detail on the management of agents including direct oral anticoagulants, digoxin, desvenlafaxine and corrosives * Updated and standardised treatment recommendations for dysrhythmias, particularly resulting from drug-induced conduction abnormalities (QRS and QT prolongation) * Simplified and standardised approaches to management (particularly cardiovascular toxicity from a variety of agents)

Produktdetails

• Verlag: Elsevier Australia
• 4 ed
• Seitenzahl: 560
• Erscheinungstermin: 16. August 2022
• Englisch
• Abmessung: 127mm x 191mm x 25mm
• Gewicht: 568g
• ISBN-13: 9780729544368
• ISBN-10: 0729544362
• Artikelnr.: 63658542

Inhaltsangabe

CHAPTER 1 APPROACH TO THE POISONED PATIENT 1.1 Overview 1.2 Resuscitation
1.3 Risk assessment 1.4 Supportive care and monitoring 1.5 Investigations
1.6 Gastrointestinal decontamination 1.7 Enhanced elimination 1.8 Antidotes
1.9 Description
CHAPTER 2 SPECIFIC CONSIDERATIONS 2.1 Coma 2.2 Hypotension 2.3 Seizures
2.4 Approach to delirium 2.5 Serotonin toxicity 2.6 Anticholinergic
toxicity 2.7 Cholinergic toxicity 2.8 Neuroleptic malignant syndrome
2.9 Alcohol use disorder 2.10 Amphetamine use disorder  2.11 Opioid use
disorder 2.12 Sedative-hypnotic use disorder 2.13 Solvent abuse 2.14 Body
packers and stuffers 2.15 Osmolar gap 2.16 Acid-base disorders  2.17 The
12-lead ECG in toxicology 2.18 Approach to mushroom poisoning 2.19 Approach
to plant poisoning 2.20 Poisoning during pregnancy and lactation
2.21 Poisoning in children 2.22 Poisoning in the elderly
CHAPTER 3 SPECIFIC TOXINS 3.1 Alcohol: Ethanol 3.2 Alcohol: Ethylene glycol
3.3 Alcohol: Isopropanol (isopropyl alcohol) 3.4 Alcohol: Methanol (methyl
alcohol) 3.5 Alcohol: Other toxic alcohols 3.6 Amisulpride 3.7 Amphetamines
and amphetamine-like substances 3.8 Angiotensin-converting enzyme
inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs)
3.9 Anticoagulant rodenticides 3.10 Anticonvulsants: Newer agents
3.11 Antihistamines (non-sedating) 3.12 Antihistamines (sedating)
3.13 Arsenic 3.14 Baclofen 3.15 Barbiturates 3.16 Benzodiazepines
3.17 Benztropine 3.18 Beta-blockers 3.19 Bupropion 3.20 Button batteries
3.21 Calcium channel blockers (CCBs) 3.22 Cannabinoids and synthetic
cannabinoid receptor agonists (SCRAs) 3.23 Carbamazepine 3.24 Carbon
monoxide 3.25 Chloroquine and hydroxychloroquine 3.26 Chloral hydrate
3.27 Clonidine and other central ?2-adrenergic agonists 3.28 Clozapine
3.29 Cocaine 3.30 Colchicine 3.31 Corrosives 3.32 Cyanide 3.33 Digoxin:
Acute overdose 3.34 Digoxin: Chronic poisoning 3.35 Diphenoxylate-atropine
3.36 Direct oral anticoagulants 3.37 Gamma-hydroxybutyrate (GHB)
3.38 Glyphosate 3.39 Hydrocarbons 3.40 Hydrofluoric acid 3.41 Hydrogen
peroxide 3.42 Insulin 3.43 Iron 3.44 Isoniazid 3.45 Lamotrigine 3.46 Lead
3.47 Lithium: Acute overdose 3.48 Lithium: Chronic poisoning 3.49 Local
anaesthetic agents 3.50 Mercury 3.51 Metformin 3.52 Methotrexate
3.53 Mirtazapine 3.54 Monoamine oxidase inhibitors (MAOIs)
3.55 Non-steroidal anti-inflammatory drugs (NSAIDs) 3.56 Olanzapine
3.57 Opioids 3.58 Organochlorines 3.59 Organophosphorus agents
(organophosphates and carbamates) 3.60 Paracetamol: Immediate-release
preparations (acute overdose) 3.61 Paracetamol: Modified-release
formulations 3.62 Paracetamol: Repeated supratherapeutic ingestion
3.63 Paraquat 3.64 Phenothiazines and butyrophenones (antipsychotic agents)
3.65 Phenytoin 3.66 Potassium chloride 3.67 Pregabalin 3.68 Quetiapine 
3.69 Quinine 3.70 Risperidone 3.71 Salicylates 3.72 Selective serotonin
reuptake inhibitors (SSRIs) 3.73 Strychnine 3.74 Sulfonylureas
3.75 Theophylline 3.76 Thyroxine 3.77 Tramadol and tapentadol
3.78 Tricyclic antidepressants (TCAs) 3.79 Valproic acid (sodium
valproate)  3.80 Venlafaxine and desvenlafaxine 3.81 Warfarin
CHAPTER 4 ANTIDOTES 4.1 Atropine 4.2 Calcium 4.3 Cyproheptadine
4.4 Desferrioxamine 4.5 Digoxin immune fab 4.6 Dimercaprol 4.7 DMSA
(succimer) and DMPS (unithiol) 4.8 Ethanol 4.9 Flumazenil 4.10 Folinic acid
4.11 Fomepizole 4.12 Glucose 4.13 Hydroxocobalamin 4.14 Insulin (high-dose)
4.15 Intravenous lipid emulsion 4.16 Methylene blue 4.17 N-acetylcysteine
4.18 Naloxone  4.19 Octreotide 4.20 Penicillamine 4.21 Physostigmine
4.22 Pralidoxime 4.23 Pyridoxine 4.24 Sodium bicarbonate 4.25 Sodium
calcium edetate 4.26 Sodium thiosulfate 4.27 Vitamin K
CHAPTER 5 ENVENOMINGS 5.1 Approach to snakebite 5.2 Black snake 5.3 Brown
snake 5.4 Death adder 5.5 Tiger snake group 5.6 Taipan 5.7 Sea snakes
5.8 Australian scorpions 5.9 Bluebottle jellyfish (Physalia species)
5.10 Stonefish 5.11 Box jellyfish 5.12 Irukandji syndrome 5.13 Blue-ringed
octopus 5.14 Redback spider 5.15 Funnel-web (big black) spider
5.16 White-tailed spider 5.17 Ticks
CHAPTER 6 ANTIVENOMS 6.1 Black Snake Antivenom 6.2 Brown Snake Antivenom
6.3 Death Adder Antivenom 6.4 Tiger Snake Antivenom 6.5 Taipan Antivenom
6.6 Sea Snake Antivenom 6.7 Polyvalent Snake Antivenom 6.8 Stonefish
Antivenom 6.9 Box Jellyfish Antivenom 6.10 Redback Spider Antivenom
6.11 Funnel-Web Spider Antivenom 6.12    Allergic Reactions to Antivenom