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This study shows the changes in the salivary physio chemical proprieties among diabetes patients with poor metabolic control. The saliva is considered a non-invasive method to detect the inflammatory bio markers like salivary Interleukin-6, Interleukin-1 Receptor Antagonist, Secretory Leukocyte Peptidase Inhibitor, matrix metalloproteinase which may be considered an indicator of oral health status and glycemic control in type-I diabetes mellitus.