The Proteasomal System in Aging and Disease

Volume 109
Herausgegeben:Grune, Tilman

• Gebundenes Buch

Produktbeschreibung

This volume of Progress in Molecular Biology and Translational Science discusses cutting-edge research of proteasomes and proteasome-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure, function, and regulation of the proteasomal system. The second part describes the role of the proteasome in aging and disease.

Produktdetails

• Progress in Molecular Biology and Translational Science Volume 109
• Verlag: Academic Press
• Artikelnr. des Verlages: C2010-0-66760-5
• Seitenzahl: 436
• Erscheinungstermin: 5. Juli 2012
• Englisch
• Abmessung: 237mm x 161mm x 30mm
• Gewicht: 662g
• ISBN-13: 9780123978639
• ISBN-10: 0123978637
• Artikelnr.: 36538774

Inhaltsangabe

1. Structure of the Proteasome


Tobias Jung and Tilman Grune


2. Structure and Function of the Ubiquitin-Proteasome System: Modulation of Components


Niki Chondrogianni and Efstathios S. Gonos


3. Immunoproteasomes: Structure, Function, and Antigen Presentation


Deborah A. Ferrington and Dale S. Gregerson


4. Interactions of the Proteasomal System with Chaperones - Protein Triage and Protein Quality Control


Marc Kästle and Tilman Grune


5. Proteasome Inhibitors


Boris Cvek


6. Degradation of Damaged Proteins - The Main Function of the 20S Proteasome


Andrew. M. Pickering and Kelvin. J. A. Davies


7. Changes of the Proteasomal System During the Aging Process


Martin A. Baraibar and Bertrand Friguet


8. Proteasome and Cancer


Betul Catalgol


9. The Ubiquitin Proteasome System and Cardiovascular Disease.


Saul R. Powell, Joerg Herrmann, Amir Lerman, Cam Patterson, Xuejun Wang


10. Role of the Ubiquitin-Proteasome in Protein Quality Control and Signaling: Implication in the Pathogenesis of Eye Diseases


Fu Shang and Allen Taylor


11. Proteasome and Neurodegenerative Diseases

Betul Catalgol and Tilman Grune

Rezensionen

Praise for the series: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal