Neue Einblicke in die Mechanismen der normalen und anormalen Skelettentwicklung verspricht dieser hochaktuelle neue Band der exzellenten Novartis-Reihe. Ansätze aus der Molekulargenetik des Menschen, Entwicklungsbiologie, Zell- und Gewebebiologie sowie der Biochemie der Signalweiterleitung verbinden sich hier zu einem breitgefächerten Bild. Auf dieser Basis wird die Äthiologie genetischer Erkrankungen, die das Skelett beeinflussen, besser verständlich. (07/00)
Neue Einblicke in die Mechanismen der normalen und anormalen Skelettentwicklung verspricht dieser hochaktuelle neue Band der exzellenten Novartis-Reihe. Ansätze aus der Molekulargenetik des Menschen, Entwicklungsbiologie, Zell- und Gewebebiologie sowie der Biochemie der Signalweiterleitung verbinden sich hier zu einem breitgefächerten Bild. Auf dieser Basis wird die Äthiologie genetischer Erkrankungen, die das Skelett beeinflussen, besser verständlich. (07/00)
Gail Cardew is the editor of The Molecular Basis of Skeletogenesis, published by Wiley. Jamie Goode is a British author with a PhD in plant biology, and a wine columnist of The Sunday Express. Goode also contributes to wine publications such as Harpers, The World of Fine Wine, Decanter, GrapesTALK and Sommelier Journal.
Inhaltsangabe
Introduction (B. Hall). Genetic Control of Skeletal Development (G. Karsentry). Early Steps in Limb Patterning and Chondrogenesis (S. Pizette & L. Niswander). General Discussion I. Developmental Mechanisms of Vertebrate Limb Evolution (M. Cohn). Regulation of Chondrocyte Growth and Differentiation by Fibroblast Growth Factor Receptor (D. Ornitz). Defects of Human Skeletogenesis--Models and Mechanisms (S. Mundlos). Genetic Control of the Cell Proliferation--Differentiation Balance in the Developing Skull Vault: Roles of Fibroblast Growth Factor Receptor Signalling Pathways (G. Morriss-Kay, et al.). Craniosynostosis and Related Limb Anomalies (A. Wilkie, et al.). The Parathyroid Hormone-Related Protein and Indian Hedgehog Feedback Loop in the Growth Plate (H. Kronenberg & U. Chung). Cartilage Matrix Resorption in Skeletogenesis (W. Wu, et al.). Retinoid signalling and skeletal development (T. Underhill, et al.). General Discussion II. Defects in Extracellular Matrix Structural Proteins in the Osteochondrodysplasias (D. Cohn). Genetic Control of Bone and Joint Formation (D. Kingsley). The Molecular Basis of Osteoclast Differentiation and Activation (T. Suda, et al.). Clinical Disorders of Bone Resorption (G. Russell, et al.). Final Discussion. Index of Contributors. Subject Index.
Introduction (B. Hall). Genetic Control of Skeletal Development (G. Karsentry). Early Steps in Limb Patterning and Chondrogenesis (S. Pizette & L. Niswander). General Discussion I. Developmental Mechanisms of Vertebrate Limb Evolution (M. Cohn). Regulation of Chondrocyte Growth and Differentiation by Fibroblast Growth Factor Receptor (D. Ornitz). Defects of Human Skeletogenesis--Models and Mechanisms (S. Mundlos). Genetic Control of the Cell Proliferation--Differentiation Balance in the Developing Skull Vault: Roles of Fibroblast Growth Factor Receptor Signalling Pathways (G. Morriss-Kay, et al.). Craniosynostosis and Related Limb Anomalies (A. Wilkie, et al.). The Parathyroid Hormone-Related Protein and Indian Hedgehog Feedback Loop in the Growth Plate (H. Kronenberg & U. Chung). Cartilage Matrix Resorption in Skeletogenesis (W. Wu, et al.). Retinoid signalling and skeletal development (T. Underhill, et al.). General Discussion II. Defects in Extracellular Matrix Structural Proteins in the Osteochondrodysplasias (D. Cohn). Genetic Control of Bone and Joint Formation (D. Kingsley). The Molecular Basis of Osteoclast Differentiation and Activation (T. Suda, et al.). Clinical Disorders of Bone Resorption (G. Russell, et al.). Final Discussion. Index of Contributors. Subject Index.
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