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Laboratory animals, including rats, play an important role in biomedical research and advances. As such, the humane care and management of these animals is an ongoing concern. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the laboratory setting. The second edition of this bestseller has been thoroughly expanded and updated. The new edition now features full-color illustrations to provide greater clarity to the techniques and concepts discussed. The text serves as a valuable, handy reference for both experienced individuals and for those without extensive training in working with the rat.