This book brings together current information on the families that make up the kinesin superfamily of molecular motors in one comprehensive text; an ideal reference for reseachers looking to make comparisons between different familiies, for specific information on a family, or simply for an overview of the kinesin superfamily.
This book brings together current information on the families that make up the kinesin superfamily of molecular motors in one comprehensive text; an ideal reference for reseachers looking to make comparisons between different familiies, for specific information on a family, or simply for an overview of the kinesin superfamily.
Claire T. Friel earned a BSc in Biochemistry from the University of Glasgow, UK, and carried out her PhD work on protein folding kinetics in the laboratory of Sheena Radford at the University of Leeds, UK. In 2006, she joined the group of Jonathon Howard at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. There, she solved the ATP turnover cycle of the microtubule depolymerising Kinesin-13, MCAK, and developed an interest in the kinesin superfamily of molecular motors. Since 2011, Claire has held the position of Assistant Professor at the University of Nottingham, UK. The research goals of the Friel lab are to understand the relationship between the kinesin motor domain sequence and the many functional properties of the kinesin superfamily and to understand the molecular mechanisms of proteins that regulate microtubule dynamics.
Inhaltsangabe
Contents Acknowledgements....................................................................................................ix Editor bio...................................................................................................................xi List of Contributors................................................................................................. xiii Chapter 1 Introduction to the Kinesin Superfamily..............................................1 Hannah R. Belsham and Claire T. Friel Chapter 2 The Kinesin-1 Family: Long-Range Transporters.............................. 15 David D. Hackney and Alison E. Twelvetrees Chapter 3 The Kinesin-2 Family: Transporters................................................... 33 William O. Hancock Chapter 4 The Kinesin-3 Family: Long-Distance Transporters.......................... 41 Nida Siddiqui and Anne Straube Chapter 5 The Kinesin-4 Family......................................................................... 55 Claire T. Friel Chapter 6 The Kinesin-5 Family: Transporters and Creators.............................65 Mary Popov, Alina Goldstein-Levitin and Larisa Gheber Chapter 7 The Kinesin-6 Family.........................................................................83 Claire T. Friel Chapter 8 The Kinesin-8 Family.........................................................................87 Tianyang Liu, Alejandro Peña, Fiona Shilliday, and Carolyn A. Moores Chapter 9 The Kinesin-13 Family: Specialist Destroyers.................................. 101 Julie P. Welburn and Claire T. Friel Chapter 10 The Kinesin-14 Family...................................................................... 115 Marcus Braun, Stefan Diez and Zdenek Lansky Chapter 11 The Kinesin-15 Family...................................................................... 135 Hauke Drechsler, Jaspreet Singh Grewal and Andrew D. McAinsh Chapter 12 The Kinesin-16 Family...................................................................... 155 Hanan M. Alghamdi and Claire T. Friel Chapter 13 Other Kinesin Families..................................................................... 161 Claire T. Friel Chapter 14 Summary and Future Perspectives.................................................... 165 Claire T. Friel Index....................................................................................................................... 167
Contents Acknowledgements....................................................................................................ix Editor bio...................................................................................................................xi List of Contributors................................................................................................. xiii Chapter 1 Introduction to the Kinesin Superfamily..............................................1 Hannah R. Belsham and Claire T. Friel Chapter 2 The Kinesin-1 Family: Long-Range Transporters.............................. 15 David D. Hackney and Alison E. Twelvetrees Chapter 3 The Kinesin-2 Family: Transporters................................................... 33 William O. Hancock Chapter 4 The Kinesin-3 Family: Long-Distance Transporters.......................... 41 Nida Siddiqui and Anne Straube Chapter 5 The Kinesin-4 Family......................................................................... 55 Claire T. Friel Chapter 6 The Kinesin-5 Family: Transporters and Creators.............................65 Mary Popov, Alina Goldstein-Levitin and Larisa Gheber Chapter 7 The Kinesin-6 Family.........................................................................83 Claire T. Friel Chapter 8 The Kinesin-8 Family.........................................................................87 Tianyang Liu, Alejandro Peña, Fiona Shilliday, and Carolyn A. Moores Chapter 9 The Kinesin-13 Family: Specialist Destroyers.................................. 101 Julie P. Welburn and Claire T. Friel Chapter 10 The Kinesin-14 Family...................................................................... 115 Marcus Braun, Stefan Diez and Zdenek Lansky Chapter 11 The Kinesin-15 Family...................................................................... 135 Hauke Drechsler, Jaspreet Singh Grewal and Andrew D. McAinsh Chapter 12 The Kinesin-16 Family...................................................................... 155 Hanan M. Alghamdi and Claire T. Friel Chapter 13 Other Kinesin Families..................................................................... 161 Claire T. Friel Chapter 14 Summary and Future Perspectives.................................................... 165 Claire T. Friel Index....................................................................................................................... 167
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