This book for the first time comprehensively surveys the research investigating the Jak-Stat pathway and its role in normal blood development as well as its perturbation in disease. It draws on the expertise of world-renowned medical researchers to take the reader from basic biology through to recent therapeutic advances.
This book for the first time comprehensively surveys the research investigating the Jak-Stat pathway and its role in normal blood development as well as its perturbation in disease. It draws on the expertise of world-renowned medical researchers to take the reader from basic biology through to recent therapeutic advances.
1. Jaks and Normal Hematopoiesis; T. Nosaka.2. Jak3-Dependent Pathways in Hematopoiesis and SCID; N.A. Cacalano, J.A. Johnston.3. Stat Activation by Src, Fes and Btk Tyrosine Kinases; T.E. Smithgall.4. Stats and Hematopoiesis; A.C. Ward.5. Stat Signaling in Leukemia: Implications for Pathogenesis and Treatment; D.A. Frank.6. The Role of the Jak-Stat Pathway in Hematopoiesis and Immune Responses in Drosophila; E.A. Bach, N. Perrimon.7. SOCS Proteins in Hematopoiesis; S. Nicholson, W. Alexander. Index.
1. Jaks and Normal Hematopoiesis; T. Nosaka.2. Jak3-Dependent Pathways in Hematopoiesis and SCID; N.A. Cacalano, J.A. Johnston.3. Stat Activation by Src, Fes and Btk Tyrosine Kinases; T.E. Smithgall.4. Stats and Hematopoiesis; A.C. Ward.5. Stat Signaling in Leukemia: Implications for Pathogenesis and Treatment; D.A. Frank.6. The Role of the Jak-Stat Pathway in Hematopoiesis and Immune Responses in Drosophila; E.A. Bach, N. Perrimon.7. SOCS Proteins in Hematopoiesis; S. Nicholson, W. Alexander. Index.
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