The Genetics and Prevalance of ¿ Thalessemia - Valampuri John, Kavitha
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Thalassemia is a disorder of haemoglobin synthesis which is characterized by the absence or reduced synthesis of globin chains. Most frequently, this disorder is found in the malarial, tropical and sub-tropical regions of Mediterranean countries, the Middle East, Transcaucasus, Central Asia, the Indian Subcontinent (South Asia) and Southeast Asia. The two main types of thalassemia are and beta-thalassemia. beta-thalassemia a common genetic disorder caused by mutations in one or more of the beta-globin gene loci that result in reduced beta-globin production. Recently, more than 200 different…mehr

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Produktbeschreibung
Thalassemia is a disorder of haemoglobin synthesis which is characterized by the absence or reduced synthesis of globin chains. Most frequently, this disorder is found in the malarial, tropical and sub-tropical regions of Mediterranean countries, the Middle East, Transcaucasus, Central Asia, the Indian Subcontinent (South Asia) and Southeast Asia. The two main types of thalassemia are and beta-thalassemia. beta-thalassemia a common genetic disorder caused by mutations in one or more of the beta-globin gene loci that result in reduced beta-globin production. Recently, more than 200 different mutations have been detected affecting the diverse levels of beta -globin gene expression and cause beta-thalassaemia. This book explores the different mutations causing beta thalassemia and the geographical distribution and racial origin.
Autorenporträt
Current Position: Assistant Professor, Department of Biotechnoogy, Mother Teresa Women's University.Specialization: Medical Genomics, Immunogenetics, Population Genomics.Publications: More than 25 publications in peer reviewed international journals.Presentation: More than 50 paper presentations in national and international conferences.