Jonathan M. Meyer (San Diego University of California), Stephen M. Stahl (San Diego University of California)

The Clozapine Handbook

Stahl's Handbooks

• Broschiertes Buch

Produktbeschreibung

Clozapine is the only effective antipsychotic for treatment resistant schizophrenia and other severe mental illnesses, but is underutilized partly due to clinician unfamiliarity with monitoring principles and side-effect management. This Handbook provides clinically focussed approaches and logic for clinicians to manage clozapine-treated patients.

Produktdetails

• Stahl's Essential Psychopharmacology Handbooks
• Verlag: Cambridge University Press
• Seitenzahl: 326
• Erscheinungstermin: 16. Mai 2019
• Englisch
• Abmessung: 185mm x 121mm x 17mm
• Gewicht: 364g
• ISBN-13: 9781108447461
• ISBN-10: 1108447465
• Artikelnr.: 55293339

Autorenporträt

Jonathan M. Meyer is currently a Clinical Professor of Psychiatry at the University of California, San Diego and a Psychopharmacology Consultant to the California Department of State Hospitals. Dr Meyer is an internationally recognised speaker on psychopharmacology and the treatment of severe mental illness, and is Distinguished Fellow of the American Psychiatric Association.

Inhaltsangabe

Preface; 1. Initiating Clozapine; 2. Understanding hematologic monitoring and benign ethnic neutropenia; 3. Binding profile
metabolism
kinetics
drug interactions and use of plasma levels; 4. Managing constipation; 5. Managing sialorrhea; 6. Managing sedation
orthostasis and tachycardia; 7. Managing metabolic adverse effects; 8. Managing seizure risk and stuttering; 9. Fever
myocarditis
interstitial nephritis
DRESS
serositis and cardiomyopathy; 10. Eosinophilia
leukocytosis
thrombocytopenia
thrombocytosis
anemia
hepatic function abnormalities; 11. Managing enuresis and incontinence
priapism
venous thromboembolism
neuroleptic malignant syndrome
tardive dyskinesia and obsessive compulsive disorder; 12. The efficacy story: treatment resistant schizophrenia
psychogenic polydipsia
treatment intolerant schizophrenia
suicidality
violence
mania and Parkinson's disease psychosis; 13. Addressing clozapine positive symptom nonresponse in schizophrenia spectrum patients; 14. Discontinuing clozapine and management of cholinergic rebound; 15. Special topics: child and adolescent patients
elderly patients
patients with intellectual disability
pregnancy and risk for major congenital malformation
lactation
overdose
postmortem redistribution; Index.