David Machin (ed.)

Textbook of Clinical Trials

Herausgegeben von Machin, David

• Gebundenes Buch

Produktbeschreibung

Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: ". very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas.

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Textbook of Clinical Trials second edition continues the original aim, to highlight the varied ways that clinical trials - particularly randomized controlled trials - have influenced the practice of medicine within different therapeutic areas. It describes the different challenges posed by those conducting clinical trials across a range of medical specialities and allied fields and at the same incorporates the development of clinical trial statistical methodology. The background to each medical speciality is provided, followed by the characteristic problems experienced by trialists in that area. Case studies are used throughout to provide a comprehensive key text in this rapidly expanding area.

This unique way of presenting clinical trial information will make this second edition an essential reference for clinical trialists, whether with administrative, data management and quality, scientific, medical or statistical roles. In addition it will provide a reference for pharmaceutical industry personnel, members of ethics committees and those who work in regulatory departments.

Building on the success of the first edition many new therapeutic areas are included including:

General surgery, plastic surgery, aesthetic surgery palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal cancer thyroid cancer urological cancer

Produktdetails

• Verlag: Wiley & Sons
• 2. Aufl.
• Seitenzahl: 784
• Erscheinungstermin: 8. Januar 2007
• Englisch
• Abmessung: 254mm x 203mm x 41mm
• Gewicht: 1825g
• ISBN-13: 9780470010143
• ISBN-10: 0470010142
• Artikelnr.: 20893891

Autorenporträt

David Machin, Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore. Simon Day, Medicines and Healthcare Products Regulatory Agency, London, UK. Sylvan Green, Arizona Cancer Center, Tucson, Arizona, USA.

Inhaltsangabe

- Preface to First Edition.

- Preface to Second Edition.

- INTRODUCTION.

1 The Development of Clinical Trials (Simon Day).
2 General Statistical Issues (David Machin).
3 The Cochrane Collaboration (Mike Clarke).

- CANCER.

4 Breast Cancer (Donald A. Berry, Terry L. Smith and Aman U. Buzdar).
5 Childhood Cancer (Sharon B. Murphy and Jonathan J. Shuster).
6 Gastrointestinal Cancers (Dan Sargent, Rich Goldberg and Paul Limberg).
7 Melanoma (P.-Y. Liu and Vernon K. Sondak).
8 Respiratory Cancers (Joan H. Schiller and Kyungmann Kim).
9 Adrenal Cortical Carcinoma (I. Malik and P. Perros).
10 Thyroid Cancer (V. Arutchelvan and P. Perros).
11 Urologic Cancers (Edith D. Canby-Hagino, Catherine M. Tangen and Ian M. Thompson).
12 Haematologic Cancers: Challenges in Developing New Therapeutic Approaches (Charles A. Schiffer and Stephen L. George).

- CARDIOLOGY.

13 Acute Stroke (Philip Bath).
14 Cardiovascular Disease (Krishna Prasad).

- DENTISTRY AND ORAL HEALTH CARE.

15 Dentistry and Oral Health Care (May C.M. Wong, Colman McGrath and Edward C.M. Lo).

- DERMATOLOGY.

16 Dermatology (Luigi Naldi and Cosetta Minelli).

- INFECTIOUS DISEASES.

17 HIV Infection (Michael D. Hughes).
18 Infectious Diseases (Ingela Krantz).

- OPHTHALMOLOGY.

19 Ophthalmology (Jonathan C.K. Clarke and Peng-Tee Khaw).

- PSYCHIATRY.

20 Anxiety Disorders (M. Katherine Shear and Philip W. Lavori).
21 Cognitive Behaviour Therapy (Nicholas Tarrier and Til Wykes).
22 Psychotherapy for Depression (Graham Dunn).

- REPRODUCTIVE HEALTH.

23 Contraception (Gilda Piaggio and Timothy M.M. Farley).
24 Gynaecology and Infertility (Siladitya Bhattacharya and Jill Mollison).
25 Early Pregnancy Termination (Beverly Winikoff and Batya Elul).
26 Maternal and Perinatal Health (Jose Villar, Allan Donner, Edgardo Abalos and Liana Campódonico).

- RESPIRATORY.

27 Respiratory Medicine (Anders Källén ).
- SURGERY & ANAETHESIA.
28 Anaesthesia and Pain (Paul S. Myles and John Rigg).
29 General Surgery (Olga Jonasson and Domenic Reda).
30 Plastic Surgery - Reconstructive Surgery (Erik Ang and Woffles Wu).
31 Plastic Surgery - Aesthetic Surgery (Woffles Wu and Erik Ang).

- TRANSPLANTATION.

32 Renal Transplantation (Vathsala Anantharaman).

- OTHER PROCEDURES.

33 Wound Healing (Colin Song and Edwin Chan).
34 Palliative Care (Robert S. Krouse and David Casarett).
35 Complementary Medicine (Ping-Chung Leung).
36 Health Care Research (Randall D. Cebul, Neal V. Dawson and Thomas E. Love).
37 Nursing (Nicola Crichton).

- SPECIAL POPULATIONS.

38 Clinical Trials in Paediatrics (Johan P.E. Karlberg).
39 Clinical Trials in Older People (Carol Jagger and Anthony J. Arthur).
40 Clinical Trials in Rare Diseases (Simon Day).

- Index