Study on the Copy Number Variations of the CHKB, KLF6, GPC1 and CHRM3

Study on the Copy Number Variations of the CHKB, KLF6, GPC1 and CHRM3

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Associating copy number variations (CNVs) with growth and gene expression are a powerful approach for identifying genomic characteristics that contribute to phenotypic and genotypic variation. A previous study using next-generation sequencing illustrated that the choline kinase beta (CHKB), Krüpple-like factor 6 (KLF6), glypican 1(GPC1) and cholinergic receptor muscarinic 3 (CHRM3)genes resides within copy number variable regions (CNVRs) of yak populations that overlap with quantitative trait loci of meat quality and growth. These results confirmed the significant function of KLF6, CHKB, GPC1...