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STEMI or ST-Elevation Myocardial Infarction is a form of myocardial infarction in which a major artery of the heart is blocked. It is a serious and life-threatening medical emergency which is usually associated with atherosclerosis. Acute STEMI may lead to arrhythmias like ventricular fibrillation, and result in sudden cardiac arrest. At this stage, defibrillation and cardiopulmonary resuscitation are required to restore a normal heart rhythm. Nausea, vomiting, chest discomfort, anxiety, diaphoresis and palpitations are signs of a STEMI. An ECG may support a STEMI diagnosis if ST elevation is observed. It is usually treated with thrombolytics or with the aid of a percutaneous coronary intervention. This procedure is known as angioplasty or stenting. This book elucidates the concepts and innovative models around the diagnosis and treatment of STEMI. The topics included on STEMI are of utmost significance and bound to provide incredible insights to readers. In this book, using case studies and examples, constant effort has been made to make the understanding of the difficult concepts as easy and informative as possible, for the readers.