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Bachelor Thesis from the year 2022 in the subject Sociology - Children and Youth, grade: Final Year, Osun State University (Global Affairs and Sustainable Development Institute), course: Sociology, language: English, abstract: Drug misuse among youths creates harm to social and biological lifestyles, yet affects legitimate economic activities in society. In spite of the fact that poly-drug use and illegal use of drug is a crime, many youths still indulged in it due to the merriment moment they derive from it. In the light of these, some selected youth in Ede, Osun State made it known to the researcher that they consume drugs to reason well or meditate and to eliminate phobia. Not only that, but illicit drugs use among youths has ravaged Nigeria. The social and biological implications of drugs prevailing in the area and especially the knowledge and attitude to drug usage, the types of drugs being consumed, drug use pattern and evolving risk behaviour and factors influencing the usage of drugs among youth, thus seem worth of exploration. It is on this basis that this study examined the social and biological implication of drug usage among youths in Ede, Osun State. A questionnaire was the main instrument adopted to collect data for the study. A multistage sampling technique was adopted to reach the respondents as a result of which 200 residents of Ede at these selected communities: Orita fogo, Sagba joint, Abogunde Joint, Orita Akala, Atapara joint, Sabo agbongbe, Oke Obada joint, Owode-Ede joint, Laoye joint, Agate, Joint and Isibo Joint in Osun State were involved in the study. At the end of data collection, 200 copies of the questionnaire were retrieved and treated for data analysis. The data generated were analysed and interpreted with the aid of tabular distribution of respondents and simple frequency with percentage.