This book describes all aspects of the technique of small-angle scattering of X-rays and neutrons, including instrumentation, sample requirements, data interpretation and modelling methods, in a comprehensive way and gives examples of applications in various fields of biophysics and biochemistry.
This book describes all aspects of the technique of small-angle scattering of X-rays and neutrons, including instrumentation, sample requirements, data interpretation and modelling methods, in a comprehensive way and gives examples of applications in various fields of biophysics and biochemistry.
Dmitri I.Svergun: MSc in Solid state physics (1980), Physics Department, Moscow State University, Russia; PhD in Physics and Mathematics (1982) and Dr. of Science (1997), Institute of Crystallography, Moscow, Russia; Engineer, Researcher, Senior Scientist at the Institute of Crystallography, Russian Academy of Sciences, Moscow (1980 - 2008); Guest scientist, GKSS Research Centre, Geesthacht, Germany (1990-1991); Visitor, Staff Scientist, Group Leader, at the European Molecular Biology Laboratory Hamburg Outstation (1991-present). Michel, H.J. Koch: PhD in chemistry, University of Louvain (1970), Neutron scattering on biological macromolecules in solution (1974-1976). Consultant (1975-1976), Group leader at the European Molecular Biology Laboratory outstation at DESY, Hamburg (1977-2006), Visiting professor at the Faculty of Engineering and Natural Science, Sabanci University, Turkey (2008-2009) and the Chemistry Department, University of Leuven (2006 - present). Roland May: Diploma in Physics (Technische Universität München); Thesis work at the Max-Planck Institut für Biochemie, Martinsried; PhD Technische Universität München 1978; scientist in the Large-Scale Structures group of the Institut Laue-Langevin, Grenoble until 2008; retired. Peter Timmins: BSc in Chemistry (1967), MSc in Crystallography (1968) and PhD in Crystallography (1972) - Birkbeck College, University of London. Instrument Scientist, Institut Laue-Langevin, 1975 - 1993, Head, Large Scale Structures Group, Institut Laue-Langevin, 1993 - 2010. Since 2010, retired.
Inhaltsangabe
* Introduction * PART I. THEORY AND EXPERIMENT * 1: Basics of small-angle scattering * 2: X-ray and neutron scattering instruments * 3: Experimental practice and data processing * PART II. DATA ANALYSIS METHODS * 4: Monodisperse systems * 5: Polydisperse and interacting systems * PART III. BIOLOGICAL APPLICATIONS OF SOLUTION SAS * 6: Static structral studies * 7: Kinetic and perturbation studies * 8: Analysis of interparticle interactions * 9: SAS in multidisciplinary studies * Conclusions and future outlook * Appendix 1: Waves, complex number, Fourier transforms, convolution, correlation * Appendix 2: Spherical harmonics formalism * Appendix 3: Interactions between spherical molecules * Appendix 4: List of Web resources * Introduction * PART I. THEORY AND EXPERIMENT * 1: Basics of small-angle scattering * 2: X-ray and neutron scattering instruments * 3: Experimental practice and data processing * PART II. DATA ANALYSIS METHODS * 4: Monodisperse systems * 5: Polydisperse and interacting systems * PART III. BIOLOGICAL APPLICATIONS OF SOLUTION SAS * 6: Static structral studies * 7: Kinetic and perturbation studies * 8: Analysis of interparticle interactions * 9: SAS in multidisciplinary studies * Conclusions and future outlook * Appendix 1: Waves, complex number, Fourier transforms, convolution, correlation * Appendix 2: Spherical harmonics formalism * Appendix 3: Interactions between spherical molecules * Appendix 4: List of Web resources
* Introduction * PART I. THEORY AND EXPERIMENT * 1: Basics of small-angle scattering * 2: X-ray and neutron scattering instruments * 3: Experimental practice and data processing * PART II. DATA ANALYSIS METHODS * 4: Monodisperse systems * 5: Polydisperse and interacting systems * PART III. BIOLOGICAL APPLICATIONS OF SOLUTION SAS * 6: Static structral studies * 7: Kinetic and perturbation studies * 8: Analysis of interparticle interactions * 9: SAS in multidisciplinary studies * Conclusions and future outlook * Appendix 1: Waves, complex number, Fourier transforms, convolution, correlation * Appendix 2: Spherical harmonics formalism * Appendix 3: Interactions between spherical molecules * Appendix 4: List of Web resources * Introduction * PART I. THEORY AND EXPERIMENT * 1: Basics of small-angle scattering * 2: X-ray and neutron scattering instruments * 3: Experimental practice and data processing * PART II. DATA ANALYSIS METHODS * 4: Monodisperse systems * 5: Polydisperse and interacting systems * PART III. BIOLOGICAL APPLICATIONS OF SOLUTION SAS * 6: Static structral studies * 7: Kinetic and perturbation studies * 8: Analysis of interparticle interactions * 9: SAS in multidisciplinary studies * Conclusions and future outlook * Appendix 1: Waves, complex number, Fourier transforms, convolution, correlation * Appendix 2: Spherical harmonics formalism * Appendix 3: Interactions between spherical molecules * Appendix 4: List of Web resources
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