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Americans should be served by a healthcare system that consistently delivers reliable performance. Every healthcare provider must be constantly improving systematically and seamlessly, with each care experience and transition. Patient safety, quality outcomes, and medical liability are key challenges health systems and caregivers are facing today. The Telluride Experience unleashes a systematic, evidence-based education that achieves striking results in safety, quality, leadership, and healthcare value. This program successfully addresses a deep need for transformational patient safety and quality improvement education. It is our hope that every reader, student or patient, will become an effective advocate for patient safety and quality in healthcare.