Safety of Synthetic food colorant Tartrazine is in Question

Safety of Synthetic food colorant Tartrazine is in Question

Pharmaceutical Analysis

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An efficient and accurate Reverse Phase High Performance Liquid Chromatographic method was developed and validated for the separation and determination of synthetic food colorant Tartrazine(E102)in certain food stuff and in drugs. This method was successfully applied for the estimation of tartrazine dye in certain food stuff (cream biscuits, Tang, gems, and candies) and in drugs (Aceclofenac and Metoprolol tablets - in which tartrazine was present as a coating agent). Interaction study was carried out to find the effect of tartrazine on the protein binding of Drugs in Bovine serum albumin. The...