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Heberprot-P® (Herber-Biotec, Cuba) is a genetically engineered epidermal growth factor, an effective drug for the healing of diabetic foot ulcers. Its administration, along with metabolic control, reduces the risk of amputation and improves health-related quality of life (HRQoL). It refers specifically to the health of the individual, and is used to designate the concrete outcomes of clinical assessment and therapeutic decision-making. The new edition of this book expands the information through instruments that assess HRQoL, reflecting the patient's subjective perception of the impact of the disease itself and the treatment administered on the dimensions of their health status.