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Pyrazolo[3,4-d]pyrimidines are substances that found applications in medical practice (allopurinol) and have a number of biological activities: antimicrobial, antiinflammatory, anticancer, etc. Methods of synthesis, including both variants of pyrazole nucleus annulation by pyrimidine ring and pyrimidine nucleus by pyrazole ring, chemical and biological properties of pyrazolo[3,4-d]pyrimidine, and methods of their synthetic usage for the construction of synthetic polycyclic systems have been analyzed and generalized in the review.

Produktbeschreibung
Pyrazolo[3,4-d]pyrimidines are substances that found applications in medical practice (allopurinol) and have a number of biological activities: antimicrobial, antiinflammatory, anticancer, etc. Methods of synthesis, including both variants of pyrazole nucleus annulation by pyrimidine ring and pyrimidine nucleus by pyrazole ring, chemical and biological properties of pyrazolo[3,4-d]pyrimidine, and methods of their synthetic usage for the construction of synthetic polycyclic systems have been analyzed and generalized in the review.
Autorenporträt
Doctor of chemical Sciences, professor, Head of the department of the medical and pharmaceutical chemistry of Bukovinian State Medical University (c.Chernivtsi), area research interests -chemistry pyrazole, bioorganic chemistry.