Protein Phosphatases

Herausgegeben:Arino, Joaquín; Alexander, Denis

• Broschiertes Buch

Produktbeschreibung

This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in our understanding of the molecular basis of cell biology and of pathological processes.

The book covers dephosphorylation processes involving serine/threonine, as well as tyrosine and histidine residues, and aims to be a useful resource for both the advanced reader as well as the newcomer to the field. It is also valuable for those working in the pharmaceutical and Biotech industries.

Produktdetails

• Topics in Current Genetics 5
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-642-05817-2
• Softcover reprint of hardcover 1st ed. 2004
• Seitenzahl: 396
• Erscheinungstermin: 10. April 2011
• Englisch
• Abmessung: 235mm x 155mm x 22mm
• Gewicht: 599g
• ISBN-13: 9783642058172
• ISBN-10: 3642058175
• Artikelnr.: 32055654

Inhaltsangabe

Overview of Protein Serine/Threonine Phosphatases.- Protein Phosphatase 1.- Protein Phosphatase 2A: A Multifunctional Regulator of Cell Signaling.- Calcineurin: Roles of the Ca2+/Calmodulin-dependent Protein Phosphatase in Diverse Eukaryotes.- Roles of Mammalian Protein Phosphatase 2C Family Members in the Regulation of Cellular Functions.- PP5: the TPR Phosphatase.- Protein Histidine Phosphatases in Signal Transduction and Metabolism.- Anchoring of Protein Kinase and Phosphatase Signaling Units.- Functional Proteomics in Phosphatase Research.- Structure and Function of the T-cell Protein Tyrosine Phosphatase.- Protein Tyrosine Phosphatase-based Therapeutics: Lessons From PTP1B.- The CD45 Phosphotyrosine Phosphatase.- Receptor Protein Tyrosine Phosphatases.- The Shp-2 Tyrosine Phosphatase.- SHP-1 Twelve Years on: Structure, Ligands, Substrates and Biological Roles.- The Dual-specific Protein Tyrosine Phosphatase Family.- Tyrosine Phosphatases in Cancer: Targets for Therapeutic Intervention.