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This book is a non-profit publication. It was printed in large font, which let older people and vision-impaired persons read it easier. It has 10 individual chapters. There is an open letter to Nobel Prize winners and world leaders in English and Chinese. The author claimed that the selfish gene is a group of genes including membrane systhesis genes, membrane shaping genes and self-recognition genes. Selfish gene has great importance in the evolution and natural selection process. Human being's society was developed from individualism to familism, to nationalism and finally to the Homo sepiansism. The current leaders of various nations couldn't lead the future world, because they are only patriotisms, that does not put the highest benefit to the whole human beings. It is urgent to establish the "World Leaders Education Institute" to nurse the future world leaders, and postpone the doomsday. Gao's equation E=7B2^44 is very important in explanation of why there shall appear three tides of worldwide immigration before the doomsday. The woman's womb is the general switch for the ultimate longevity of mankind.