Prognosis of in-vitro transdermal permeation using in silico modelling - Sapra, Bharti;Silakari, Om;Goyal, Neha
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Skin permeation of molecules is a multifactorial phenomenon depending on diverse types of physical, chemical and biological interactions.In vitro skin permeation studies are frequently performed for screening of molecules and drug carrier systems aimed at optimizing dermal or transdermal delivery. Mathematical models often aid directly by providing information on the rate of drug penetration through the skin and thus on dermal or system concentration of drugs. They are also helpful in analyzing experimental data, reducing the no. of experiments and translating the in vitro setting.

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Produktbeschreibung
Skin permeation of molecules is a multifactorial phenomenon depending on diverse types of physical, chemical and biological interactions.In vitro skin permeation studies are frequently performed for screening of molecules and drug carrier systems aimed at optimizing dermal or transdermal delivery. Mathematical models often aid directly by providing information on the rate of drug penetration through the skin and thus on dermal or system concentration of drugs. They are also helpful in analyzing experimental data, reducing the no. of experiments and translating the in vitro setting.
Autorenporträt
O Dr. Bharti Sapra está a trabalhar como Professor Assistente no Departamento de Ciências Farmacêuticas e Investigação de Medicamentos, Universidade de Punjabi. Ela tem mais de trinta artigos em revistas de reputação internacional. A sua área de investigação é o desenvolvimento da formulação de novos sistemas de administração de medicamentos. Aakriti Chopra está a fazer o seu MBBS da Faculdade de Medicina Baroda, Vadodara.