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The menace of Humman Immunodeficiency virus acting alone is enormous. More complicated is a combination of both Humman Immunodeficiency virus and Hepatitis C virus occurring together in an individual. These two viruses unfortunately share common routes for transmission and therefore coinfection of both viruses has been found to be prevalent among HIV infected individuals. Coinfection worsens and quickens the evolution of HCV related liver disease in the coinfected, leading to morbidity and mortality in them. Insight into potent modes of transmission of these two viruses then helps to gain better control in disease prevention and management of the coinfected. This therefore has necessitated this work in an African setting where most infections are thought to be endemic. Dr Tunji Oyewole MB;BS,FWACP.