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The medicinal potential of a polyherbal formulation is larger and longer than that of a single plant. As a consequence, Alstonia scholaris, Centella asiatica, Corchorus trilocularis, and Morinda pubescens leaves were used to create Polyherbal Antidiabetic Sustained Release Matrix Tablets. The following plants were chosen after a thorough review of the literatureExhaustive literature was done on Plants having traditional use on anti-diabetic activity. Based on a literature review, four plants were chosen for polyherbal formulation: Alstonia scholaris, Centella asiatica, Corchorus trilocularis, and Morinda pubescens. Plants had been collected and verified. Soxhlet extraction with hydroalcoholic solvent (Ethanol 70: Water 30) is used, to dried medicinal plants that have been collected. Phytochemical analysis of Alstonia scholaris, Centella asiatica, Corchorus trilocularis, and Morinda pubescens leaf extracts revealed the presence of many phytoconstituents. All extracts had peaks of marker phytoconstiuents on HPTLC, indicating their purity.The research had two goals: first to establish the anti-diabetic properties of the extract and secondly to develop and standardize formulation.