The book addresses how biological cells work, and specifically achieve their remarkable sensing and signaling properties using insights from physics and engineering. The book aims to teach concepts, omitting many of the technical details, and hence should attract a broad readership.
The book addresses how biological cells work, and specifically achieve their remarkable sensing and signaling properties using insights from physics and engineering. The book aims to teach concepts, omitting many of the technical details, and hence should attract a broad readership.
At Imperial College Robert Endres heads the Biological Physics Group. Recently he won the prestigious ERC Strating Grant award. Before moving to the United Kingdom, Robert was a postdoc with Prof. Ned Wingreen in the Molecular Biology Department at Princeton University, where his main research accomplishments were the understanding of the remarkable signalling properties of bacterial chemotaxis and the atomistic prediction of protein-DNA binding sites.
Inhaltsangabe
1: Preface 2: Introduction 3: Physical concepts 4: Mathematical tools 5: Chemotaxis in bacterium Escherichia coli 6: Signal amplification and integration 7: Robust precise adaptation 8: Polar receptor localization and clustering 9: Accuracy of sensing 10: Motor impulse response 11: Optimization of pathway 12: 'Seeing' like a bacterium 13: Beyond E. coli chemotaxis