Phylogenomics

Foundations, Methods, and Pathogen Analysis
Herausgeber: Mokrousov, Igor; Shitikov, Egor

• Broschiertes Buch

Produktbeschreibung

Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.

Produktdetails

• Verlag: Elsevier Health Sciences
• Seitenzahl: 520
• Erscheinungstermin: 1. Juni 2024
• Englisch
• Abmessung: 235mm x 191mm
• ISBN-13: 9780323998864
• ISBN-10: 0323998860
• Artikelnr.: 67523228

Inhaltsangabe

PART I. GENERAL TOPICS AND FOUNDATIONS 1. Phylogenomic analysis and the
origin and early evolution of viruses 2. Application of Next Generation
Sequencing for Genetic and Phenotypic Studies of Bacteria 3. Genomic
insight into deciphering bacterial outbreaks 4. Drug resistance in
bacteria, molecular mechanisms and evolution 5. Virulence evolution of
bacterial species PART II. METHODS IN THE PHYLOGENOMICS 6. Modeling
evolutionary changes of k-mer patterns of bacterial genomes 7. Clock Rates
and Bayesian Evaluation of Temporal Signal 8. Microbial evolutionary
reconstruction in the presence of mosaic sequences 9. Tools for SNP calling
and the way to deal with big datasets PART III. PHYLOGENOMICS OF SPECIFIC
PATHOGENS 10. Phylogenomics of Yersinia pestis 11. Salmonella Phylogenomics
12. The phylogenomics of Shigella spp. 13. Phylogenomic diversity within
Corynebacterium diphtheriae, a re-emerging threat to global public health
14. Phylogenomics of the East Asian lineage of Mycobacterium tuberculosis
15. Mycobacterium kansasii 16. Taxonomy and phylogenomics of Leptospira 17.
Phylogenomics and evolution of Measles virus 18. Phylogenomics of HIV-1 19.
Respiratory syncytial virus 20. Phylogenomics of Flaviviruses 21. How
clonal is Staphylococcus aureus? 22. Genomic research of ancient pathogens
in Central Asia 23. Subspecific nomenclature of the Cryptococcus
neoformans/gattii complex and the predominant clonal evolution (PCE) model
24. Phylogenomics of Mycobacterium leprae