Offers readers an in-depth look into the support and implementation of existing medical technology used for patient care in a clinical setting Provides basic insights into the clinical engineering profession, focusing on engineering principles as applied to the US healthcare system Explores healthcare technology basics, hospital and systems safety, information technology and interoperability with medical devices, clinical facilities management, and human resource management in an HTM team
Offers readers an in-depth look into the support and implementation of existing medical technology used for patient care in a clinical setting Provides basic insights into the clinical engineering profession, focusing on engineering principles as applied to the US healthcare system Explores healthcare technology basics, hospital and systems safety, information technology and interoperability with medical devices, clinical facilities management, and human resource management in an HTM team
I: INDUCTION AND PATTERNING OF THE CNS AND PNS 1. Morphogens, Patterning Centers, and their Mechanisms of Action Edwin Shinichi Monuki 2. Telencephalon Patterning Shubha Tole and Jean Hébert 3. Area Patterning of the Mammalian Neocortex Elizabeth A. Grove 4. Patterning of Thalamus Guillermina López-Bendito 5. Midbrain Patterning: Polarity Formation of the Tectum, Midbrain Regionalization, and Isthmus Organizer Harukazu Nakamura 6. Cerebellar Patterning Hitoshi Komuro 7. Spinal Cord Patterning Catarina Catela 8. The Formation and Maturation of Neuromuscular Junctions Gregorio Valdez 9. Neural Induction of Embryonic Stem/Induced Pluripotent Stem Cells Anindita Sarkar, Maria Carol Marchetto and Fred H. Gage 10. Cerebral organoids Orly Reiner and Eyal Karzburn 11. Formation of gyri and sulci Katherine Long and Wieland B. Huttner II: GENERATION OF NEURONAL DIVERSITY 12. Cell Biology of Neuronal Progenitor Cells Qin Shen 13. Notch and Neural Development Joshua J. Breunig 14. bHLH Factors in Neurogenesis and Neuronal Subtype Specification Jane Johnson 15. The Specification and Generation of Neurons in the Ventral Spinal Cord Michael Matise and Kamal Sharma 16. Neurogenesis in the Cerebellum Kathleen J Millen 17. The Generation of Midbrain Dopaminergic Neurons Sandra Blaess and Siew-Lan Ang 18. Neurogenesis in the Basal Ganglia Kenneth James Campbell 19. Specification of Cortical Projection Neurons: Transcriptional Mechanisms Jeffrey D. Macklis 20. The Generation of Cortical Interneurons Gordon Fishell and Renata Batista-Brito 21. Specification of Retinal Cell Types Bernadett Bosze, Robert B. Hufnagel and Nadean L. Brown 22. Neurogenesis in the Postnatal VZ-SVZ and the Origin of Interneuron Diversity Arturo Alvarez-Buylla 23. Neurogenesis in the Damaged Mammalian Brain Masato Nakafuku 24. Neurogenesis in the Nematode Caenorhabditis elegans Oliver Hobert 25. Development of the Drosophila melanogaster embryonic CNS: From neuroectoderm to unique neurons and glia Stefan Thor 26. Neurogenesis in Zebrafish Laure Bally-Cuif 27. Gene regulatory networks controlling neuronal diversity: epigenetics/lncRNAs/enhancers Jason T. Lambert, Jessica Haigh and Alex S. Nord 28. Post-transcriptional and translational control of neurogenesis Debra Silver 29. Human neurogenesis: single cell sequencing and in vitro modeling (cerebral organoids) Arnold Kriegstein, Aparna Bhaduri and Madeline Andrews III: DEVELOPMENT OF GLIA, BLOOD VESSELS, CHOROID PLEXUS, IMMUNE CELLS IN THE NERVOUS SYSTEM 30. 'Glial' Biology: Has it Come to the Beginning of the End? David Rowitch and Arturo Alvarez-Buylla 31. Neural Stem Cells Among Glia Arnold Kriegstein and Arturo Alvarez-Buylla 32. Structure and Function of Myelinated Axons Matthew Rasband 33. Mechanisms of Astrocyte Development Debosmita Sardar, Anna Victoria Molofsky and Benjamin Deneen 34. Specification of Macroglia by Transcription Factors: Oligodendrocytes Michael Wegner 35. Specification of Macroglia by Transcription Factors: Schwann Cells John Svaren 36. Signaling Pathways that Regulate Glial Development and Early Migration - Oligodendrocytes Stephen Fancy and Robert H. Miller 37. Signaling Pathways that Regulate Glial Development and Early Migration - Schwann Cells Kristjan R. Jessen and Rhona Mirsky 38. Microglia Astrid E. Cardona, Katerina Akassoglou and Dimitrios Davalos 39. Ependymal cells Kazunobu Sawamoto and Nathalie Spassky 40. Meninges and Vasculature Julie Siegenthaler and Samuel Pleasure 41. Neuron-Glial Interactions: Neurotransmitter Signaling to Cells of the Oligodendrocyte Lineage Dwight Bergles 42. Nonmammalian Model Systems: Zebrafish Bruce Appel and Kelly Monk 43. Astrocyte-Synapse Interactions and Neural Circuit Regulation Nicola Allen in Glial Biology: Imaging Neuroglial Pathology In Vivo
I: INDUCTION AND PATTERNING OF THE CNS AND PNS 1. Morphogens, Patterning Centers, and their Mechanisms of Action Edwin Shinichi Monuki 2. Telencephalon Patterning Shubha Tole and Jean Hébert 3. Area Patterning of the Mammalian Neocortex Elizabeth A. Grove 4. Patterning of Thalamus Guillermina López-Bendito 5. Midbrain Patterning: Polarity Formation of the Tectum, Midbrain Regionalization, and Isthmus Organizer Harukazu Nakamura 6. Cerebellar Patterning Hitoshi Komuro 7. Spinal Cord Patterning Catarina Catela 8. The Formation and Maturation of Neuromuscular Junctions Gregorio Valdez 9. Neural Induction of Embryonic Stem/Induced Pluripotent Stem Cells Anindita Sarkar, Maria Carol Marchetto and Fred H. Gage 10. Cerebral organoids Orly Reiner and Eyal Karzburn 11. Formation of gyri and sulci Katherine Long and Wieland B. Huttner II: GENERATION OF NEURONAL DIVERSITY 12. Cell Biology of Neuronal Progenitor Cells Qin Shen 13. Notch and Neural Development Joshua J. Breunig 14. bHLH Factors in Neurogenesis and Neuronal Subtype Specification Jane Johnson 15. The Specification and Generation of Neurons in the Ventral Spinal Cord Michael Matise and Kamal Sharma 16. Neurogenesis in the Cerebellum Kathleen J Millen 17. The Generation of Midbrain Dopaminergic Neurons Sandra Blaess and Siew-Lan Ang 18. Neurogenesis in the Basal Ganglia Kenneth James Campbell 19. Specification of Cortical Projection Neurons: Transcriptional Mechanisms Jeffrey D. Macklis 20. The Generation of Cortical Interneurons Gordon Fishell and Renata Batista-Brito 21. Specification of Retinal Cell Types Bernadett Bosze, Robert B. Hufnagel and Nadean L. Brown 22. Neurogenesis in the Postnatal VZ-SVZ and the Origin of Interneuron Diversity Arturo Alvarez-Buylla 23. Neurogenesis in the Damaged Mammalian Brain Masato Nakafuku 24. Neurogenesis in the Nematode Caenorhabditis elegans Oliver Hobert 25. Development of the Drosophila melanogaster embryonic CNS: From neuroectoderm to unique neurons and glia Stefan Thor 26. Neurogenesis in Zebrafish Laure Bally-Cuif 27. Gene regulatory networks controlling neuronal diversity: epigenetics/lncRNAs/enhancers Jason T. Lambert, Jessica Haigh and Alex S. Nord 28. Post-transcriptional and translational control of neurogenesis Debra Silver 29. Human neurogenesis: single cell sequencing and in vitro modeling (cerebral organoids) Arnold Kriegstein, Aparna Bhaduri and Madeline Andrews III: DEVELOPMENT OF GLIA, BLOOD VESSELS, CHOROID PLEXUS, IMMUNE CELLS IN THE NERVOUS SYSTEM 30. 'Glial' Biology: Has it Come to the Beginning of the End? David Rowitch and Arturo Alvarez-Buylla 31. Neural Stem Cells Among Glia Arnold Kriegstein and Arturo Alvarez-Buylla 32. Structure and Function of Myelinated Axons Matthew Rasband 33. Mechanisms of Astrocyte Development Debosmita Sardar, Anna Victoria Molofsky and Benjamin Deneen 34. Specification of Macroglia by Transcription Factors: Oligodendrocytes Michael Wegner 35. Specification of Macroglia by Transcription Factors: Schwann Cells John Svaren 36. Signaling Pathways that Regulate Glial Development and Early Migration - Oligodendrocytes Stephen Fancy and Robert H. Miller 37. Signaling Pathways that Regulate Glial Development and Early Migration - Schwann Cells Kristjan R. Jessen and Rhona Mirsky 38. Microglia Astrid E. Cardona, Katerina Akassoglou and Dimitrios Davalos 39. Ependymal cells Kazunobu Sawamoto and Nathalie Spassky 40. Meninges and Vasculature Julie Siegenthaler and Samuel Pleasure 41. Neuron-Glial Interactions: Neurotransmitter Signaling to Cells of the Oligodendrocyte Lineage Dwight Bergles 42. Nonmammalian Model Systems: Zebrafish Bruce Appel and Kelly Monk 43. Astrocyte-Synapse Interactions and Neural Circuit Regulation Nicola Allen in Glial Biology: Imaging Neuroglial Pathology In Vivo
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