Nutritional Genomics
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Nutritional genomics is a science studying the relationship between human genome, nutrition and health. It can be divided into two disciplines:97% of the genes known to be associated with human diseases result in monogenic diseases, i.e. a mutation in one gene is sufficient to cause the disease. Modifying the dietary intake can prevent some monogenic diseases. One example is phenylketonuria, a genetic disease characterized by a defective phenylalanine hydroxylase enzy...
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Nutritional genomics is a science studying the relationship between human genome, nutrition and health. It can be divided into two disciplines:97% of the genes known to be associated with human diseases result in monogenic diseases, i.e. a mutation in one gene is sufficient to cause the disease. Modifying the dietary intake can prevent some monogenic diseases. One example is phenylketonuria, a genetic disease characterized by a defective phenylalanine hydroxylase enzyme, which is normally responsible for the metabolism of phenylalanine to tyrosine. This results in the accumulation of phenylalanine and its breakdown products in the blood and the decrease in tyrosine, which increases the risk of neurological damage and mental retardation. Phenylalanine-restricted tyrosine-supplemented diets are a means to nutritionally treat this monogenic disease.
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