Neurotoxicity of Drugs of Abuse, Volume Eight provides carefully crafted reviews on the disruptive impact of drugs of abuse on the central nervous system. The neurotoxicity potential of several agents including marijuana, fentanyl, and ketamine are carefully reviewed, and their short-term and chronic effects are categorized. Pharmacokinetic profiles as well as mechanisms of action for these and other drugs of abuse such as alcohol and nicotine are also evaluated. The implications of short and long-term abuse for agents such as PCP are also characterized. The reader will come away with a fuller…mehr
Neurotoxicity of Drugs of Abuse, Volume Eight provides carefully crafted reviews on the disruptive impact of drugs of abuse on the central nervous system. The neurotoxicity potential of several agents including marijuana, fentanyl, and ketamine are carefully reviewed, and their short-term and chronic effects are categorized. Pharmacokinetic profiles as well as mechanisms of action for these and other drugs of abuse such as alcohol and nicotine are also evaluated. The implications of short and long-term abuse for agents such as PCP are also characterized. The reader will come away with a fuller understanding of the adverse effects of drugs of abuse on the nervous system.
Dr. Lucio G. Costa is Professor of Toxicology at the University of Washington in Seattle, and of Pharmacology/Toxicology at the University of Parma Medical School. He received a doctorate in Pharmacology from the University of Milano in 1977, and was a postdoctoral fellow at the University of Texas at Houston. He is a member of several national and international professional organizations, a Fellow of the Academy of Toxicological Sciences, and a European Certified Toxicologist. He received various award for his scientific accomplishments, including the Achievement Award from the Society of Toxicology. He serves in various editorial capacities for several toxicology journals, and is an active manuscript and grant reviewer. Dr. Costa has been the member of dozens of panels and committees at the national and international level dealing with toxicology and risk assessment issues. He has chaired and/or organized symposia at scientific meetings in the United States and internationally.
He has been teaching classes in the area of toxicology, neurotoxicology and pharmacology to graduate and medical students for 30 years. He keeps an active research program in the area of neurotoxicology.
Inhaltsangabe
Preface William Slikker, Jr. 1. Cannabinoids G. Jean Harry 2. Converging mechanisms in ethanol neurotoxicity Miriam Beatriz Virgolini and Ricardo Marcos Pautassi 3. Neurotoxicology of nicotine and tobacco Edward D. Levin 4. The neurotoxic potential of opioids including fentanyl and fentanyl analogs R. Daniel Mellon 5. Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits Cheng Wang, Shuliang Liu, Leah E. Latham, Fang Liu, Tucker A. Patterson and William Slikker Jr 6. The mysterious beauty of ketamine: benefits and risks Donald R. Mattison, Abdallah Alami, Thomas J. Moore and G. Caleb Alexander
Preface William Slikker, Jr. 1. Cannabinoids G. Jean Harry 2. Converging mechanisms in ethanol neurotoxicity Miriam Beatriz Virgolini and Ricardo Marcos Pautassi 3. Neurotoxicology of nicotine and tobacco Edward D. Levin 4. The neurotoxic potential of opioids including fentanyl and fentanyl analogs R. Daniel Mellon 5. Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits Cheng Wang, Shuliang Liu, Leah E. Latham, Fang Liu, Tucker A. Patterson and William Slikker Jr 6. The mysterious beauty of ketamine: benefits and risks Donald R. Mattison, Abdallah Alami, Thomas J. Moore and G. Caleb Alexander
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