Ashish Ranjan

Neuronal Differentiation of Embryonic Carcinoma Cells

Differential gene expression pattern of key genes during differentiation regime

• Broschiertes Buch

Produktbeschreibung

Embryonic Carcinoma cells (EC) are malignant germ cell tumor that occurs most often in the testes.EC cells serves as a model for studying embryonic development in humans.These cells are pluripotent teratocarcinomas that are derived from transformed germ cells.EC cells are stem cells of such tumors and are generally considered to be the malignant counterparts of ES cells.The NTERA-2 cell line is pluripotent human teratocarcinoma cell.NTERA-2 shares many characteristic with human ES cell. Also, the global expression of these cells is highly similar to undifferentiated hESC expression. NTERA-2 cell as like their human counter part on treatment with Retinoic acid gets differentiated into a mixed population of cell of neuronal lineage. The study aims at monitoring the transcript abundance of genes that have previously been implicated in neuronal differentiation, namely PAX6, NOGGIN, NEUROD and NESTIN and also tries to throw some light on potential differentiation specific candidate.

Produktdetails

• Verlag: Dictus Publishing
• Seitenzahl: 60
• Erscheinungstermin: 17. Mai 2011
• Englisch
• Abmessung: 220mm x 150mm x 4mm
• Gewicht: 107g
• ISBN-13: 9783844390360
• ISBN-10: 3844390367
• Artikelnr.: 33431345

Autorenporträt

Ashish Ranjan, estudiante de doctorado en la Escuela de Terapia Regenerativa de Berlín-Brandenburgo, Maestría en Células Madre y Medicina Regenerativa de la Universidad de Manipal, India, Trabajó / Pasantía en el Instituto de Biología Médica de Singapur como Asistente de Investigación, ganó dos competencias de Quiz de Nivel Nacional, Actualmente trabaja en MDC, Berlín-Buch