Nanoparticle-Protein Corona

Biophysics to Biology
Herausgeber: Kumar, Ashutosh; Dhawan, Alok

• Gebundenes Buch

Produktbeschreibung

Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle-protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration. This book provides a detailed understanding of nanoparticle-protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle-protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.

Produktdetails

• Verlag: RSC Publishing
• Seitenzahl: 293
• Erscheinungstermin: 2. August 2019
• Englisch
• Abmessung: 236mm x 160mm x 23mm
• Gewicht: 590g
• ISBN-13: 9781788013918
• ISBN-10: 1788013913
• Artikelnr.: 54847426

Inhaltsangabe

Nanoparticle-Protein Corona Complex: Composition, Kinetics,
Physico-Chemical Characterization, and Impact on Biomedical Applications;
Biological Significance of the Nanoparticles Protein Corona; Factors
Affecting a Nanoparticle's Protein Corona Formation; NP-Protein Corona
Interaction: Characterization Methods and Analysis; An Analytical Approach
to Investigate Nanoparticle-Protein Corona Complexes; Impact of
Nanoparticle-Protein Interactions on Biological Assays; Computer
Simulations for Understanding Nanoparticle-biomolecule Corona Formation; In
Silico Approaches to Design and Characterize Peptide-based Nanostructures;
Nanomaterial-Blood Interactions: A Biomedical Perspective; The Protein
Corona: Applications and Challenges