Nanomedicine for Drug Delivery and Therapeutics

Herausgegeben von Mishra, Ajay Kumar

• Gebundenes Buch

Produktbeschreibung

This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.

Produktdetails

• Verlag: Wiley & Sons
• 1. Auflage
• Seitenzahl: 536
• Erscheinungstermin: 22. Januar 2013
• Englisch
• Abmessung: 236mm x 160mm x 33mm
• Gewicht: 9g
• ISBN-13: 9781118414095
• ISBN-10: 1118414098
• Artikelnr.: 36729639

Autorenporträt

Ajay Kumar Mishra is currently working as the Director at the Centre for Nanomaterials Science and also as an associate professor at the Department of Applied Chemistry, University of Johannesburg, South Africa, where he is a group leader of the research area for the composites/nanocomposites, water research, and bio-inorganic chemistry.

Inhaltsangabe

Preface xv Part 1: Nanomedicine 1 1 High-technology Therapy Using
Biomolecules or Synthetic Compounds for HIV Inhibition 3 Elvis
Fosso-Kankeu, Pascaline Fontehand Ajay K.Mishra 1.1 Gene Therapy Including
RNAHigh-Technology Against HIV 4 1.2 Metals and HIV Therapy 16 1.3
Conclusions 26 References 27 2 Emerging Nanomedicine Approaches for
Osteochondral Tissue Regeneration 39 Author Lineis Missing 2.1 Introduction
39 2.2 Emerging NanomedicineApproaches 42 References 54 3 Synthesis of
Poly(Methacrylate) Encapsulated Magnetite Nanoparticles via Phosphonic Acid
Anchoring Chemistry and Its Applications Toward Biomedicine 63 B.
Kothandapaniand Ajay K. Mishra 3.1 Introduction 64 3.2 Synthesis of
Magnetite Nanoparticles 73 3.3 Application in Biomedical Fields 82 3.4
Conclusions 84 References 85 4 Potentiometric PVC Membrane Sensors and
Their Analytical Applications in Pharmaceuticals and Environmental Samples
at Micro- and Nano-level 87 Gamal Abel-Hafiz Mostafa 4.1 Introduction 87
4.2 Ion Selective Electrode 88 4.3 Glass Membrane Electrode 89 4.4
Characteristics of ISE 90 4.5 Preparation of PVC Membrane 94 4.6 Method of
Preparation of the Liquid Membrane ISEs 96 4.7 Application of Ion Selective
Electrodes in Pharmaceutical and Environmental Analysis Using 97 4.8
Conclusion 123 References 127 5 Bioceramics: Silica-based Organic-Inorganic
Hybrid Materials for Medical Applications 135 Sadanand Pandey and Shivani
B. Mishra 5.1 Introduction 136 5.2 Organic-Inorganic Hybrid Materials 141
5.3 Tissue Engineering 146 5.4 Other Organic-Inorganic Bioceramics for
Medical Applications 150 5.5 Conclusion 156 5.6 Considerations and Future
Directions 157 Acknowledgement 157 References 158 6 Recent Advances of
Multifunctional Nanomedicines 163 Pradeep Pratap Singh and Ambika 6.1
Introduction 163 6.2 Nanomaterials of Biomedical Interest 164 6.3
Target-specificPharmacotherapy: Need for Nanocarrier Delivery Systems 165
6.4 Engineering of Pharmaceutical Nanosystems 166 6.5 Applications of
Pharmaceutical Nanotools 180 6.6 Nanotoxicity 181 6.7 Future prospects 182
6.8 Conclusion 183 References 184 7 Nanomedicinal Approaches for Diabetes
Management 189 Prashant Kumar Raiand Ajay Kumar Mishra 7.1 Introduction:
The Motivation behind the Chapter 189 7.2 Type of Diabetes 191 7.3
Treatments for Diabetes 192 7.4 Why the Interest in Nanomedicine Research?
193 7.5 The Vision of Nanotechnology and its Clinical Applications for
Diabetes 194 7.6 Summary 195 Acknowledgements 195 References 195 8
Polymeric Nanofibersin Regenerative Medicine 197 Narayan Chandra Mishra and
Sharmistha Mitra (Majumder) 8.1 Introduction 197 8.2 Preparation of
Nanofibers 199 8.3 RecentAdvances onApplication of Polymeric Nanofibersin
Regenerative Medicine 201 8.4 Conclusions 222 References 222 Part 2: Drug
Delivery and Therapeutics 227 9 Multifunctional Nano/Micro Polymer Capsules
as Potential 229 Haider Sami, J. Jaishree, Ashok Kumar and Sri Sivakumar
9.1 Introduction 230 9.2 Synthesis of Polymer Capsules 232 9.3 Properties
of Multilayered Polymer Capsules 237 9.4 Loading of Therapeutics 239 9.5
Stimuli-responsive Polymer Capsules 242 9.6 Multifunctional Hybrid Capsules
255 9.7 Targeted Polymer Capsules 267 9.8 BiomedicalApplications 268 9.9
Outlook and Future Prospects 274 References 274 10 Nanophosphors-Nanogold
Immunoconjugates in Isolation of Biomembranes and in Drug Delivery 285
Dwijendra Gupta, Dhruv Kumar, Manish Dwivedi, Vijay Tripathi, Pratibha
Phadke-Gupta and Surya Pratap Singh 10.1 Introduction 286 10.2 Nanoparticle
Technology 287 10.3 The Versatility of Nanoparticles in Biological Sciences
288 10.4 Materials and Methods 293 10.5 Nanotags for Bio-labeling and
Targeting: Nanophosphors or Quantum Dots 297 10.6 AFM Study of CdS and
BSATagged ZnS-Mn Nanoparticles 302 10.7 Nano-Conjugates in Drug Delivery
304 10.8 Nanoparticle-mediated Drug Delivery and Nanotherapeutics 305 10.9
The Limitations of QDs 306 10.10 Summary 307 Acknowledgements 308
References 309 11 Cyclodextrin-based Nanoengineered Drug Delivery System
313 Jaya Lakkakula and Rui Werner Maçedo Krause 11.1 Introduction 314 11.2
Inclusion Complex Formation 316 11.3 Phase Solubility Relationships 318
11.4 Effect of Cyclodextrin on Drug Formulation 321 11.5 Cyclodextrin-based
Drug Delivery 324 11.6 Cyclodextrins in Novel Drug Delivery Systems (DDS)
331 11.7 Conclusion 335 Acknowledgements 335 References 338 12 Medicinal
Patches and Drug Nanoencapsulation 343 María H. Lissarrague, Hernan Garate,
Melisa E. Lamanna, Norma B. D'Accorso and Silvia N.Goyanes 12.1
Introduction 343 12.2 Overview of Passive Skin Permeation (Passive Patches)
344 12.3 Recent Development on Skin Permeation 357 12.4 Drug Encapsulation
361 12.5 Triggered Release 369 12.6 Conclusions 374 References 374 13
Dendrimers: AClass of Polymer in the Nanotechnology for the Drug Delivery
379 Sunil K.Singh and Vivek K. Sharma 13.1 Introduction 379 13.2 Historical
Origin of Dendrimers 380 13.3 Structure of Dendrimers 381 13.4 Terms Used
in Dendrimer Chemistry 383 13.5 Types of Dendrimers 385 13.6 Application of
Dendrimers 392 13.7 Dendrimers in Oral Drug Delivery 394 13.8 Dendrimers in
Transdermal Drug Delivery 396 13.9 Dendrimers in Ocular Drug Delivery 398
13.10 Dendrimers inAnticancer Drug Delivery 399 13.11 Dendrimers in Cancer
Diagnosis and Treatment 401 13.12 Conclusion 411 References 411 14
Designing Nanocarriers for Drug Delivery 417 Munishwar N. Gupta and Joyeeta
Mukherjee 14.1 Introduction 417 14.2 Sizes, Shapes andAdvantages of
Nanomaterials 418 14.3 Bioconjugation Strategies 421 14.4 Carbon Nanotubes
429 14.5 Drug Targeting 434 14.6 Future Perspectives 436 Acknowledgements
437 References 437 15 Multifunctional Polymeric Micelles for Drug Delivery
and Therapeutics 443 Alicia Sawdon and Ching-An Peng 15.1 Introduction 443
15.2 Composition, Formation and Characterization of Polymeric Micelles 444
15.3 Polymeric Micelles for Cancer Chemotherapy 450 15.4 Targeting Schemes
457 15.5 Polymeric Micelles for Diagnostics and Imaging 465 15.6
Conclusions 467 References 467 16 Nanoparticles-based Carriers for Gene
Therapy and Drug Delivery 477 Marketa Ryvolova, Jana Drbohlavova, Kristyna
Smerkova, Jana Chomoucka, Pavlina Sobrova,Vojtech Adam, PavelKopel, Jaromir
Hubalek and Rene Kizek 16.1 Introduction 478 16.2 Targeted Delivery 478
16.3 Conclusion 494 References 494