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This study was conducted to evaluate Microtensile bond strength, nanoleakage for two dual cured self-adhesive resin cements boning zirconia to dentin. One hundred and twenty zirconia blocks were fabricated and divided into two groups one treated by100µm Al2O3 and the other one untreated. Each group was subdivided into 2 subgroups according to the types of cements used. Assemblies were further divided to 1 day, 7 days without thermocycling and 7 days with thermocycling classes.