Mycophenolate mofetil: development of an FIA assay method
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The validity of our method has been demonstrated. Routine use was successfully tested on 16 pediatric preparations of cellcept®. In the physico-chemical compatibility study, omeprazole and methylprednisolone showed a color change with the appearance of a precipitate. Other drug mixtures showed a significant change in pH, with no apparent visual disturbance. Discussion: This study contributes to the safety of the cellcept® circuit in our center, but has certain limitations. Other tests could be carried out to reinforce our results, namely turbidimetry and the development of a separating dosin...
The validity of our method has been demonstrated. Routine use was successfully tested on 16 pediatric preparations of cellcept®. In the physico-chemical compatibility study, omeprazole and methylprednisolone showed a color change with the appearance of a precipitate. Other drug mixtures showed a significant change in pH, with no apparent visual disturbance. Discussion: This study contributes to the safety of the cellcept® circuit in our center, but has certain limitations. Other tests could be carried out to reinforce our results, namely turbidimetry and the development of a separating dosing method. This study can be considered for other drugs, while improving it with the proposed complementary tests, in order to try to secure their circuits.
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