Multiparticulate Oral Drug Delivery

Herausgeber: Ghebre-Selassie, Isaac

• Broschiertes Buch

Produktbeschreibung

This definitive reference explores the various aspects of multiparticulate dosage form development-assessing the in vivo behavior and performance of multiparticulates as well as comparing their market position to other dosage forms. It discusses alternative pelletization techniques such as balling (spherical agglomeration), spray congealing, and cryopelletization. The book also covers formulation and processing variables that affect the formation, integrity, and performance of coatings derived from molten materials and polymeric solutions and dispersions and details the idiosyncrasies of the manufacturing process of hard-shell gelatin capsules.

Produktdetails

• Verlag: CRC Press
• Seitenzahl: 496
• Erscheinungstermin: 19. September 2019
• Englisch
• Abmessung: 229mm x 152mm x 38mm
• Gewicht: 839g
• ISBN-13: 9780367402044
• ISBN-10: 0367402041
• Artikelnr.: 57814498

Autorenporträt

Isaac Ghebre-Sellassie

Inhaltsangabe

Manufacture of Core Pellets by Balling
Preparation of Micropellets by Spray Congealing
Cryopelletization
Coating of Multiparticulates Using Polymeric Solutions: Formulation and
Process Considerations
Coating of Multiparticulates Using Polymeric Dispersions: Formulation and
Process Considerations
Coating of Multiparticulates Using Molten Materials: Formulation and
Process Considerations,
Suspensions and Dispersible Dosage Forms of Multiparticulates, Roland
Bodmeier and Ornlaksana Paeratakul
Multiparticulate Encapsulation Equipment and Process
Compaction of Multiparticulate Oral Dosage Forms
Key Factors in the Development of Modified-Release Pellets
Mechanisms of Release from Coated Pellets
Biopharmaceutical Aspects of Multiparticulates
In Vivo Behavior of Multiparticulate Versus Single-Unit Dose Formulations
Capsule Shell Composition and Manufacturing
Packaging of Multiparticulate Dosage Forms: Materials and Equipment
Marketing Considerations