The dream of developing a biocomputer should not be dismissed as a sheer fantasy. Although there is naturally some doubt as to whether it is possible to design a computer using carbon-based components as in living organisms, instead of silicon-based components as in existing computers, the fact that an average brain often outperforms the most sophisticated computer in terms of the complexity of tasks, if not in terms of speed, is a living testimony to this possibility. The remaining question is to what extent a biocomputer can mimic a living organism and whether it is possible to design and…mehr
The dream of developing a biocomputer should not be dismissed as a sheer fantasy. Although there is naturally some doubt as to whether it is possible to design a computer using carbon-based components as in living organisms, instead of silicon-based components as in existing computers, the fact that an average brain often outperforms the most sophisticated computer in terms of the complexity of tasks, if not in terms of speed, is a living testimony to this possibility. The remaining question is to what extent a biocomputer can mimic a living organism and whether it is possible to design and fabri cate such a biocomputer within the foreseeable future. This volume does not attempt to provide immediate and exact answers to these questions but instead attempts to provide a vision and a progress report of the initial efforts. This volume is mainly a collection of papers presented at the Symposium on Molecular Electronics - Biosensors and Biocomputers, sponsored by the Divi sion of Biotechnology, Health and Environment of the Fine Particle Society, held from July 19-22, 1989 at the Society's 19th Annual Meeting in Santa Clara, California. Also included are articles contributed by those who planned to attend the conference but were unable to do so. The emergence of the field of molecular electronics is largely the consequence of one person's crusade, that of Forrest L. Carter.
A Pioneer in Molecular Electronics.- A Pioneer in Molecular Electronics.- Fabrication of Molecular Assemblies.- Forrest L. Carter Lecture: Organized Monolayers - Building Blocks in Constructing Supramolecular Devices.- Syntheses of Electrically Conductive LB Films and Host-Guest LB Films of Cyclodextrins and Azobenzenes.- Artificial Structure of Metal Complexes by Selective Coordination Epitaxy.- Industrial Scale Production of L-B Layers.- Characterization of Molecular Assemblies.- Depth Profiling in Organic Thin Films with Optical Guided Waves.- Synchrotron X-Ray Studies on Lipid Monolayers.- Fluorescence Image Analysis of the Spatial Organization of Lipid Layers.- Electrochemical Aspect of Molecular Electronics.- Electrochemical Processes in Membrane Channels and Biosynthetic Structures.- Electroconformational Coupling: A fundamental Process of Biomolecular Electronics for Signal Transductions.- The Role of Solvent Permittivity Dispersion in Electrostatic Interactions in Proteins.- An Electrochemical Approach to the Design of Membrane-Based Molecular Optoelectronic Devices.- Metallo-Proteins and other Electroactive Molecules.- Biomolecular Electronics: Structure ? Function Relationship.- Synthetic Models for Photoinduced Electron Transfer Reactions.- Electron Transfer Rates in Mitochondrial Proteins: Regulation and Specificity.- Dye Binding to Polytryptophan and Lysine-Tryptophan copolymer: Electron Transfer Quenching by Biopol3rmer Pendant Groups.- Photoactive Interfacially Polymerized Polyporphyrin Films.- Retinal Proteins and other Pigment Proteins.- Light Energy Transducing and Signal Transducing Rhodopsins of Halobacteria.- Visual Phototransduction: Biochemical Aspects.- Biological Photosensors: Phytochrome and Stentorin.- Animal Rhodopsin as a PhotoelectricGenerator.- A Correlation between Photocycle and Photoelectric Response of Bacteriorhodopsin Monomers.- Biological Information Processing.- Neurons as Microprocessors with a Kind of Memory Function.- Phase Wave and Perception of Amoeboid Cells.- Microtubules: Possible Application to Computer Technologies.- Information Processing in Microtubules: Biomolecular Automata and Nanocomputers.- Molecular Device and Biosensor Technology.- BLM-Based Biosensors and Devices: Applications and Future Prospects.- Biomolecular Interface.- On the Volt-Ampere Characteristics of Molecular Monoelectronic Elements.- Immobilization of Nicotinamide Adenine Dinucleotide: Implications in Molecular Electronics and Bioengineering.- ISFET-Like Devices Coupled to Neuroblastoma Cells: Cytometric and Electrical Characterization.- Incorporation of Ion Channels in Polymerized Membranes and Fabrication of a Biosensor.- Molecular Sensors Based on Olfactory Transduction.- Monolayer Molecular Recognition Sites as a Basis for Biosensor Development.- Au/Langmuir-Blodgett Film/Zn Se Tunnel Injection Light-Emitting Structures.- Design of a True Molecular Electronic Device: the Electron Transfer Shift Register Memory.- Ultra High Speed Bacteriorhodopsin Photodetectors.- Optical Random Access Memory Based on Bacteriorhodopsin.- Actual Possibilities of Bacteriorhodopsin Application in Optoelectronics.- General and Theoretical Aspects of Molecular Jilectronics.- Towards the Molecular Computer Factory.- Ultralow Frequency "Optical" Biocomputers: Biophysical Arguments.- Mathematical Problems Arising in Molecular Electronics: Global Geometry and Dynamics of the Double-Well Potential.- Nanoelectronics and Scanning Tunneling Engineering.- Contributors.
A Pioneer in Molecular Electronics.- A Pioneer in Molecular Electronics.- Fabrication of Molecular Assemblies.- Forrest L. Carter Lecture: Organized Monolayers - Building Blocks in Constructing Supramolecular Devices.- Syntheses of Electrically Conductive LB Films and Host-Guest LB Films of Cyclodextrins and Azobenzenes.- Artificial Structure of Metal Complexes by Selective Coordination Epitaxy.- Industrial Scale Production of L-B Layers.- Characterization of Molecular Assemblies.- Depth Profiling in Organic Thin Films with Optical Guided Waves.- Synchrotron X-Ray Studies on Lipid Monolayers.- Fluorescence Image Analysis of the Spatial Organization of Lipid Layers.- Electrochemical Aspect of Molecular Electronics.- Electrochemical Processes in Membrane Channels and Biosynthetic Structures.- Electroconformational Coupling: A fundamental Process of Biomolecular Electronics for Signal Transductions.- The Role of Solvent Permittivity Dispersion in Electrostatic Interactions in Proteins.- An Electrochemical Approach to the Design of Membrane-Based Molecular Optoelectronic Devices.- Metallo-Proteins and other Electroactive Molecules.- Biomolecular Electronics: Structure ? Function Relationship.- Synthetic Models for Photoinduced Electron Transfer Reactions.- Electron Transfer Rates in Mitochondrial Proteins: Regulation and Specificity.- Dye Binding to Polytryptophan and Lysine-Tryptophan copolymer: Electron Transfer Quenching by Biopol3rmer Pendant Groups.- Photoactive Interfacially Polymerized Polyporphyrin Films.- Retinal Proteins and other Pigment Proteins.- Light Energy Transducing and Signal Transducing Rhodopsins of Halobacteria.- Visual Phototransduction: Biochemical Aspects.- Biological Photosensors: Phytochrome and Stentorin.- Animal Rhodopsin as a PhotoelectricGenerator.- A Correlation between Photocycle and Photoelectric Response of Bacteriorhodopsin Monomers.- Biological Information Processing.- Neurons as Microprocessors with a Kind of Memory Function.- Phase Wave and Perception of Amoeboid Cells.- Microtubules: Possible Application to Computer Technologies.- Information Processing in Microtubules: Biomolecular Automata and Nanocomputers.- Molecular Device and Biosensor Technology.- BLM-Based Biosensors and Devices: Applications and Future Prospects.- Biomolecular Interface.- On the Volt-Ampere Characteristics of Molecular Monoelectronic Elements.- Immobilization of Nicotinamide Adenine Dinucleotide: Implications in Molecular Electronics and Bioengineering.- ISFET-Like Devices Coupled to Neuroblastoma Cells: Cytometric and Electrical Characterization.- Incorporation of Ion Channels in Polymerized Membranes and Fabrication of a Biosensor.- Molecular Sensors Based on Olfactory Transduction.- Monolayer Molecular Recognition Sites as a Basis for Biosensor Development.- Au/Langmuir-Blodgett Film/Zn Se Tunnel Injection Light-Emitting Structures.- Design of a True Molecular Electronic Device: the Electron Transfer Shift Register Memory.- Ultra High Speed Bacteriorhodopsin Photodetectors.- Optical Random Access Memory Based on Bacteriorhodopsin.- Actual Possibilities of Bacteriorhodopsin Application in Optoelectronics.- General and Theoretical Aspects of Molecular Jilectronics.- Towards the Molecular Computer Factory.- Ultralow Frequency "Optical" Biocomputers: Biophysical Arguments.- Mathematical Problems Arising in Molecular Electronics: Global Geometry and Dynamics of the Double-Well Potential.- Nanoelectronics and Scanning Tunneling Engineering.- Contributors.
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