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Protozoans are interesting creatures for several reasons, not least of which is their ability to live inside or among the cells of their host while resisting the host's cellular defences. The rigours of their lifestyle have resulted in the evolution of some remarkable adaptation at the biochemical level; many parasites have dispensed with entire metabolic pathways, and have evolved complex mechanisms for transmission to new hosts. Parasitic protozoa cause some of the major infectious diseases of humans and domestic animals. In recent years, new molecular biological techniques have opened up…mehr

Produktbeschreibung
Protozoans are interesting creatures for several reasons, not least of which is their ability to live inside or among the cells of their host while resisting the host's cellular defences. The rigours of their lifestyle have resulted in the evolution of some remarkable adaptation at the biochemical level; many parasites have dispensed with entire metabolic pathways, and have evolved complex mechanisms for transmission to new hosts. Parasitic protozoa cause some of the major infectious diseases of humans and domestic animals. In recent years, new molecular biological techniques have opened up the study of the biology of these parasites, and tremendous advances have been made. This book covers this interesting and fast-moving field at an advanced level for which there is no other up-to-date book.
Frontiers in Molecular Biology is a series of books designed to report on rapidly evolving, key areas of research in molecular biology. Individual chapters are written by leading researchers who are specialists in their fields. Each book is carefully organized to provide an integrated analysis of current progress in the area covered. Parasitic protozoa cause major infectious diseases of humans and domestic animals. In recent years, new techniques in molecular biology have allowed tremendous advances in our understanding of these parasites. Molecular Biology of Parasitic Protozoa covers this fast-moving field at an advanced level for which there is no other up-to-date book. Topics covered include trypanosomatid and Toxoplasma genetics, structure and replication of kinetoplast DNA, regulation of gene expression in trypanosomes, trans-splicing, RNA editing, the three genomes of Plasmodium, mechanisms of drug resistance, biogenesis of glycosomes and hydrogenosomes, glycosylphosphatidylinositols and the surface architecture of parasitic protozoa. Molecular Biology of Parasitic Protozoa is a unique compendium of current research findings in this important area. It contains over 900 references and provides a comprehensive review of the field as well as valuable insights and predictions of future progress by leading researchers.