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This book surrounded with the microwave assisted synthesis of some new 3-substituted-pyrazol-1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives and investigation of their antimicrobial activity. The one-pot three-component, microwave assisted condensation reaction of 3-substituted-1H-pyrazole-4-carbaldehyde 1a-d with cyano-active methelene 2a-d and 2,3-dihydro-1,4-phthalazinedione 5 proceeded effortlessly in ethanol in presence of triethyl amine (TEA) as a catalyst to give corresponding 3-substituted-pyrazol-1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives in good to excellent yields.…mehr

Produktbeschreibung
This book surrounded with the microwave assisted synthesis of some new 3-substituted-pyrazol-1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives and investigation of their antimicrobial activity. The one-pot three-component, microwave assisted condensation reaction of 3-substituted-1H-pyrazole-4-carbaldehyde 1a-d with cyano-active methelene 2a-d and 2,3-dihydro-1,4-phthalazinedione 5 proceeded effortlessly in ethanol in presence of triethyl amine (TEA) as a catalyst to give corresponding 3-substituted-pyrazol-1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives in good to excellent yields. So, it is admirable to express brief about synthetic and biological significance of the phthalazine.
Autorenporträt
Vala, Nileshkumar Dhirubhai
Expert in organic synthesis and characterization.