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This book deals with Nursing that is a vital aspect of the health care system, and nurses are vital members of health care. Nursing is facing new development in the 21st century. In a wide variety of settings, nurses are increasingly likely to care for patients on mechanical ventilators. The nurses are challenged to make quick yet critical decisions in the rapidly expanding health care system relating to the provision of quality care to the clients with mechanical ventilators. The quality of care is attainable through nursing practice which becomes the cornerstone for nursing education, service and research. We have discussed in this book, Mechanical ventilators, concepts of ventilation, principles of ventilator care, standards of care to the patients with mechanical ventilators.