Pey-Chang Kent Lin, Sunil P. Khatri

Logic Synthesis for Genetic Diseases

Modeling Disease Behavior Using Boolean Networks

• Broschiertes Buch

Produktbeschreibung

This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful implicit enumeration techniques. Coverage also includes techniques from VLSI testing to control a faulty BN, transforming its behavior to a healthy BN, potentially aiding in efforts to find the best candidates for treatment of genetic diseases.

Produktdetails

• Verlag: Springer / Springer New York / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4939-5535-0
• Softcover reprint of the original 1st ed. 2014
• Seitenzahl: 100
• Erscheinungstermin: 23. August 2016
• Englisch
• Abmessung: 234mm x 156mm x 7mm
• Gewicht: 201g
• ISBN-13: 9781493955350
• ISBN-10: 1493955357
• Artikelnr.: 45574359

Inhaltsangabe

Introduction.- Part I Inference of Gene Regulatory Networks.- Predictor Set Inference using SAT.- Determining Gene Function in Boolean Networks using SAT.- Predictor Ranking using Modified Zhegalkin Functions.- Part II Intervention of Gene Regulatory Networks.- ATPG for Cancer Therapy.- Summary and Future Work.