Living Donor Organ Transplantation

Herausgeber: Gruessner, Rainer W G; Benedetti, Enrico

• Gebundenes Buch

Produktbeschreibung

Living Organ Donor Transplantation, Second Edition puts the entire discipline in perspective while guiding readers step-by-step through the most common organ transplant surgeries. Organized into four cohesive parts and featuring numerous surgical illustrations, this sourcebook delivers an incisive look at every key consideration for general surgeons who perform transplantations, from patient selection to recipient workup and outcomes, and emphasizes the most humanitarian approaches. Sections provide content on living donor uterus transplantation, new operative techniques, including the use of robotic and minimally invasive transplant procedures, new immunosuppressive regimens, new protocols of tolerance induction including stem cell therapy and transplantation, and much more. Chapter authors are international leaders in their fields and represent institutions from 4 continents (Americas: USA, Argentina, Brazil, Canada; Europe: France, Germany, Italy, Spain, Sweden, UK; Asia: China, Japan, Korea, Taiwan; Australia).

Produktdetails

• Verlag: Elsevier Science
• 2nd edition
• Seitenzahl: 1100
• Erscheinungstermin: 24. November 2023
• Englisch
• Abmessung: 276mm x 216mm
• ISBN-13: 9780323899260
• ISBN-10: 0323899269
• Artikelnr.: 65507971

Inhaltsangabe

PART I. GENERAL ASPECTS OF LIVING DONOR ORGAN TRANSPLANTATION
1. Introduction and Rationale
2. Cultural Differences In Living Organ Donation
2.1. A Global Perspective
2.2. The United States Experience
2.2.1 Racial Disparities in Living Donor Transplant
2.2.2 Cultural Differences in Living Organ Donation: The United States
Experience: Hispanics
2.3. Cultural Differences in Living Organ Donation: The European East-West
Difference Regarding Organ Transplantation
3. Ethical and Legal Issues
3.1. The American Perspective
3.2. The Asian Perspective
3.2.1. East Asia
3.2.2. India
3.2.3. Near and Middle East
3.3. The European Perspective
3.4. Ethical and Legal Issues: UNOS and Living Donation: Present and Future
Donor Policies
4. Donor Counseling and Consent
4.1. Ethically teaching and testing living organ donors
4.2. Donor Counseling and Consent: Informed Consent
4.3. Donor Counseling and Consent: Donor Advocate
5. Nondirected Donors
6. General Aspects of Living Donor Organ Transplantation: Social Issues
PART II. PAID LEGAL AND ILLEGAL ORGAN DONATION
7. Current Financial Incentives
7.1. Current Financial Incentives: Incentives in Western Countries
7.2. Current Financial Incentives: Incentives in Non-Western Countries -
The Iranian Model
7.3. Current Financial Incentives: Impact of Government-Sponsored Financial
Reimbursement of Expenses
8. Paid Legal Organ Donation
8.1. A Regulated System of Incentives for Living Kidney Donation - PRO
8.2. Paid Legal Organ Donation: Pro - The Philosopher's Perspective
8.3. Paid Legal Organ Donation: Con- The Clinician's Perspective
8.4. Paid Legal Organ Donation: Con- The Ethicist's Perspective
9. Challenges of Paid Organ Donation for Public Health Care Policy
10. Who's Got the Knife? The Role of Surgeons in Transplant Trafficking
PART III. THE ROLE OF SOCIAL MEDIA
11. Living Donor Organ Transplantation: The Role of Public Solicitation
12. The Impact of the Internet and Social Media on Paid Legal and Illegal
Organ Donation
PART IV. ORGAN-SPECIFIC ASPECTS OF LIVING DONOR ABDOMINAL ORGAN
TRANSPLANTATION
SECTION I. KIDNEY TRANSPLANTATION
13. Kidney Transplantation: Personal Reflections
14. History of Living Donor Kidney Transplantation
15. Kidney Transplantation: Geographical Differences
16. Preemptive Living Transplantation: The Ideal Therapeutic Modality for
End-Stage Renal Disease
17. KIDNEY TRANSPLANTATION: THE DONOR
17.1. Kidney Transplantation - The Donor: Selection and Workup
17.2. Kidney Transplantation - The Donor: The Marginal Donor
17.3. Kidney Transplantation - The Donor: The Hepatitis C Positive Donor
17.4. Kidney Transplantation - The Donor: Infection Transmission from
Donors Including COVID-19
17.5. Kidney Transplantation - The Donor: Immunologic Evaluation and
Histocompatibility
17.6. Kidney Transplantation - The Donor: Anesthesiologic Management
17.7. Surgical Procedures
17.7.1. Kidney Transplantation - The Donor, Surgical Procedures: Open
Standard Nephrectomy
17.7.2. Kidney Transplantation: Minimally Invasive Open Donor Nephrectomy
'Mini-nephrectomy'
17.7.3. Kidney Transplantation - The Donor, Surgical Procedures:
Transperitoneal Laparoscopic Nephrectomy
17.7.4. Retroperitoneal Laparoscopic Nephrectomy
17.7.5. Kidney Transplantation - The Donor, Surgical Procedures: Robotic
Nephrectomy
17.7.6. Living Donor Nephrectomy Techniques: Comparative Review and
Critical Appraisal
17.7.7. Vaginal Donor Nephrectomy
17.8. Kidney Transplantation - The Donor: Peri-operative Care of the Living
Kidney Donor
17.9. Kidney Transplantation - The Donor: Donor Morbidity and Mortality
17.10. Kidney Transplantation - Living Kidney Donor: Long-Term Medical
Outcomes
17.11 Kidney Transplantation - Living Kidney Donor: Long-Term Psychosocial
Outcomes
17.12. Kidney Transplantation - The Donor: Psychological Aspects
17.13. Kidney Transplantation - The Donor: International Living Donor
registry
17.14  Kidney Transplantation - The Donor: Clinical Trial on Tolerance
Induction in Living Donor Kidney Transplantation
18. KIDNEY TRANSPLANTATION: THE RECIPIENT
18.1. Kidney Transplantation - The Recipient: Selection and Workup
18.2. Kidney Transplantation - The Recipient: Anesthesiologic Management
18.3. Kidney Transplantation - The Recipient: Surgical Procedures
18.3.1. Kidney Transplantation - The Recipient, Surgical Procedures: Open
Procedures
18.3.2. Kidney Transplantation - The Recipient, Surgical Procedures:
Robotic Procedures
18.3.3. Laparoscopic and Robotic Kidney Transplant with Vaginal Insertion
of the Graft
18.4. Kidney Transplantation - The Recipient: Ischemia and Reperfusion
Injury
18.5. Kidney Transplantation - The Recipient: Perioperative Care
18.6. Kidney Transplantation - The Recipient: Posttransplant Complications
18.7. Kidney Transplantation - The Recipient: Immunosuppressive Therapy
18.8. Kidney Transplantation - The Recipient: Immunobiology
18.9. Kidney Transplantation - The Recipient: Molecular Fingerprinting and
Omics
18.10. Kidney Transplantation - The Recipient: Biomarkers of Tolerant
Patients
18.11. Kidney Transplantation - The Recipient: Recurrence of Disease
18.12. Kidney Transplantation - The Recipient: APOL 1 and Donor/Recipient
Risk of Graft Failure
18.13. Kidney Transplantation - The Recipient: Retransplantation
18.14. Kidney Transplantation - The Recipient:  Pediatric Transplantation
18.14.1. Medical Aspects of the Pediatric Kidney Recipient
18.14.2. Kidney Transplantation - The Recipient: Surgical Technique and
Complications
18.15. Kidney Transplantation - The Recipient: Long-Term Outcome
18.16. Kidney Transplantation - The Recipient, Living Donor Kidney
Transplantation And Malignancy
18.17. Kidney Transplantation - The Recipient, Strategies to Maximize the
Donor Pool
18.17.1. Kidney Transplantation - The Recipient, Strategies to Maximize the
Donor Pool: Options Available to Recipients with Incompatible Donors
18.17.2. ABO-Incompatible Kidney Transplantation
18.17.3. Kidney Transplantation - The Recipient, Strategies to Maximize the
Donor Pool: Living Donor Exchange
18.17.4. Kidney Transplantation - The Recipient: Desensitization Protocols
for High-PRA recipients
18.17.5. Kidney Transplantation - The Recipient, Strategies to Maximize the
Donor Pool: Auxiliary Liver Transplants for Highly Sensitized Kidney
Recipients
19. Kidney Transplantation: Cost Analysis
SECTION II. PANCREAS TRANSPLANTATION
20. History of and Rationale for Pancreas Transplantation
20.1. History of living Donor Pancreas Transplantation
20.2. Rationale for Living Donor Pancreas Transplants
21. Pancreas Transplantation: The Donor
21.1. Pancreas Transplantation - The Donor: Selection and Workup
21.2. Pancreas Transplantation - The Donor: Surgical Procedures and
Perioperative Care
21.2.1. Pancreas Transplantation - The Donor, Surgical Procedures and
Perioperative Care: Standard Open Distal Pancreatectomy
21.2.2. Pancreas Transplantation - The Donor, Surgical Procedures and
Perioperative Care: Laparoscopic Donor Distal Pancreatectomy
21.2.3. Pancreas Transplantation - The Donor, Surgical Procedures and
Perioperative Care: Robotic Donor Distal Pancreatectomy
21.3. Pancreas Transplantation - The Donor: Morbidity, Mortality, and
Long-Term Outcome
22. Pancreas Transplantation: The Recipient
22.1. Pancreas Transplantation: The Recipient: Selection and Workup
22.2. Pancreas Transplantation - The Recipient: Surgical Procedures
22.3. Pancreas Transplantation - The Recipient: Perioperative Care,
Immunosuppressive Therapy, and Posttransplant Complications
22.4. Pancreas Transplantation - The Recipient: The Identical Twin
Transplant Experience - Recurrence of Disease
23. The Asian Experience
24. International Pancreas Registry Report (IPTR) and Long-Term Outcome
25. Islet Autotransplantation after Pancreatectomy
25.1. Islet Autotransplantation After Pancreatectomy: History and Surgical
Techniques of Total Pancreatectomy with Islet Autotransplantation (TPIAT)
25.2. Islet Autotransplantation After Pancreatectomy: Islet Isolation
25.3. Islet Autotransplantation After Pancreatectomy: Short and Long-Term
Outcome
26. Islet Transplantation Using Living Donors
SECTION III. LIVER TRANSPLANTATION
27. Personal Reflections and History of Living Donor Liver Transplantation
28. The Impact of the A2all Study
29. Regional Variations in the U.S. Living Donor Experience
30. Institutional Needs for Living Donor Liver Transplantation
31. Role of Split Liver Transplantation from Deceased Donors: Lessons
Learned
32. Liver Regeneration
33. Living Donor Liver Transplantation: The Donor
33.1. Living Donor Liver Transplantation - The Donor: Selection and Workup
33.2. Living Donor Liver Transplantation - The Donor: All in One MRI Donor
Evaluation
33.3. Living Donor Liver Transplantation - The Donor: Anesthesiologic
Management
33.4. Living Donor Liver Transplantation - The Donor: Surgical Procedures
33.4.1. Living Donor Liver Transplantation - The Donor, Surgical
Procedures: Adult Donor to Adult Recipient, Right Lobe
33.4.2. Living Donor Liver Transplantation - The Donor, Surgical
Procedures: Adult Donor to Adult Recipient, Extended Right Lobe
33.4.3. Living Donor Liver Transplantation - The Donor, Surgical
Procedures: Adult Donor to Adult Recipient, Left Lobe
33.4.4. Living Donor Liver Transplantation - The Donor, Surgical
Procedures: Adult Donor to Pediatric Recipient
33.4.5. Living Donor Liver Transplantation - The Donor, Surgical
Procedures: Laparascopic Donor Hepatectomy for the Pediatric Recipient
33.4.6. Living Donor Liver Transplantation - The Donor, Surgical
Procedures: Laparoscopic Donor Procedures for the Adult Recipient
33.4.7. Living Donor Liver Transplantation - The Donor, Surgical
Procedures: Robotic Donor Procedures for the Pediatric Recipient
33.4.8. Living Donor Liver Transplantation - The Donor, Surgical
Procedures: Robotic Donor Procedures for the Adult Recipient
33.5. Living Donor Liver Transplantation - The Donor: Perioperative Care
33.6. Living Donor Liver Transplantation - The Donor: Donor Morbidity and
Mortality
33.7. Living Donor Liver Transplantation - The Donor:  Long-Term Donor
Outcomes
33.8. Living Donor Liver Transplantation - The Donor: Psychological Aspects
34. Liver Transplantation: The Recipient
34.1. Living Donor Liver Transplantation - Recipient Selection
34.2. Liver Transplantation: The Recipient:  Anesthesiologic Management
34.3. Liver Transplantation: The Recipient: Surgical Procedures
34.3.1. Liver Transplantation - The Recipient, Surgical Procedures: Right
Lobe Liver Transplant
34.3.2. Extended Right Lobe Transplant
34.3.3. Left Lobe Transplant with and without the Caudate Lobe
34.3.4. Difficult Hepatic Artery Reconstruction in Living Donor Liver
Transplantation
34.3.5. Liver Transplantation - The Recipient, Surgical Procedures:
Difficult Biliary Reconstruction
34.3.6. Liver Transplantation - The Recipient, Surgical Procedures:
Optimized Venous Outflow
34.3.7. Liver Transplantation - The Recipient, Surgical Procedures: The
Pediatric Recipient
34.3.8. Double Liver Transplants
34.3.9. Monosegment Grafts
34.3.10. Liver Transplantation - The Recipient, Surgical Procedures:
Auxiliary Liver Transplants
34.3.11 Pure laparoscopic living donor hepatectomy in Pediatric LDLT
34.4. Liver Transplantation - The Recipient: Ischemia and Reperfusion
Injury
34.5. Liver Transplantation - The Recipient:  Small-for-size-grafts
34.6. Liver Transplantation - The Recipient:  Perioperative Care of the
Adult Liver Recipient
34.7. Liver Transplantation - The Recipient: Perioperative Care of the
Pediatric Liver Recipient
34.8. Liver Transplantation - The Recipient: Liver Transplantation and
Complications
34.9. Liver Transplantation - The Recipient: Interventional Therapies
34.10. Liver Transplantation - The Recipient: Immunosuppressive Therapy in
Liver Transplantation
34.11. Liver Transplantation - The Recipient: Immunobiology
34.12. Liver Transplantation - The Recipient: Specific Indications
34.12.1. Liver Transplantation - The Recipient, Specific Indications:
Hepatitic C
34.12.2. Liver Transplantation - The Recipient, Specific Indications:
Cancer
34.12.3. Liver Transplantation - The Recipient, Specific Indications:
Alcohol Abuse
34.12.4. Liver Transplantation - The Recipient, Specific Indications: Acute
Liver Failure
34.13. Domino Liver Transplantation
34.13.1. Liver Transplantation - The Recipient, Domino Liver
Transplantation: Technical Aspects
34.13.2. Liver Transplantation - The Recipient, Domino Liver
Transplantation: Report from the Domino Liver Transplant Registry
34.14. Liver Retransplantation
34.14.1. Liver Retransplantation: The Recipient: Adult Recipient
34.14.2. Liver Retransplantation: The Recipient: Pediatric Recipient
34.15. Long-Term Outcome
34.15.1. Liver Transplantation - The Recipient, Long-Term Outcome: Adult
Recipient
34.15.2. Liver Transplantation - The Recipient, Long-Term Outcome:
Pediatric Recipient
34.16. Strategies To Maximize The Donor Pool: Abo Incompatibility
35. Liver Transplantation: Cost Analysis
SECTION IV. INTESTINAL TRANSPLANTATION
36. History of Living Donor Intestinal Transplantation
37. Indications for Living Donor Intestinal (and Liver) Transplantation
38. Intestinal Transplantation - The Donor
38.1. Intestinal Transplantation - The Donor: Selection and Workup
38.2. Intestinal Transplantation - The Donor: Surgical Procedures and
Perioperative Care
39. Intestinal Transplantation - The Recipient
39.1. Intestinal Transplantation - The Recipient: Selection and Workup
39.2. Intestinal Transplantation - The Recipient: Surgical Procedures and
Perioperative Care
39.3. Intestinal Transplantation - The Recipient: Sequential and
Simultaneous Intestinal and Liver Transplants - Indications, Techniques and
Outcome
39.4. Intestinal Transplantation - The Recipient: Immunosuppressive
Therapy, Immunobiology Therapy and Postoperative Complications
39.5. Intestinal Transplantation - The Recipient: Long-Term Outcomes
39.6. Intestinal Transplantation - The Recipient: Registry Report
SECTION V. UTERUS TRANSPLANTATION
40. History of Living Donor Uterus Transplantation
41. Uterus Transplantation - The Donor
41.1. Uterus Transplantation - The Donor: Selection and Workup
41.2. Uterus Transplantation - The Donor: Surgical Procedures,
Perioperative Care and Postoperative Complications
41.3. Uterus Transplantation - The Donor: Robotic And Laparoscopic
Procedures
42. Uterus Transplantation - The Recipient
42.1. Uterus Transplantation - The Recipient: Indication, Selection and
Workup
42.2. Uterus Transplantation - The Recipient: Psychosocial Assessment
42.3. Uterus Transplantation - The Recipient: Surgical Procedures and
Perioperative Care
42.4. Uterus Transplantation - The Recipient: Immunosuppressive Therapy and
Postoperative Complications
42.5. Uterus Transplantation - The Recipient: From Living Donor Uterus
Transplantation to Live Birth Obstetrical Management
42.6. Uterus Transplantation - The Recipient: Global Results Of Living
Donor Uterus Transplantation
42.7. Uterus Transplantation - The Recipient: Should Uterus Transplantation
be Publicly Funded?
PART V. FUTURE DEVELOPMENTS AND ALTERNATIVES TO LIVING DONOR
TRANSPLANTATION
43. Dual-Organ Donation and Transplantation
44. Use of Living Donors for HIV-Positive Transplant Candidates
45. New Immunosuppressive Protocols
46. Strategies to Induce Tolerance
47. Xenotransplantation
48. Gene Therapy
49. Organogenesis and related approaches for organ replacement
50. Consensus Conferences on Living Donor Organ Transplantation
50.1. Consensus Conferences on Living Donor Organ Transplantation:
Commentary: The Istanbul Declaration On Organ Trafficking And Transplant
Tourism
50.2. Consensus Conferences on Living Donor Organ Transplantation:
Commentary: The Amsterdam And Vancouver Conferences On Living Organ
Donation
51. Impact of the Coronavirus Pandemic on Living Donor Organ
Transplantation