Laboratory Hematology Practice
Herausgegeben von Kottke-Marchant, Kandice; Davis, Bruce
Laboratory Hematology Practice
Herausgegeben von Kottke-Marchant, Kandice; Davis, Bruce
- Gebundenes Buch
- Merkliste
- Auf die Merkliste
- Bewerten Bewerten
- Teilen
- Produkt teilen
- Produkterinnerung
- Produkterinnerung
Expertly edited and endorsed by the International Society for Laboratory Hematology, this is the newest international textbook on all aspects of laboratory hematology. Covering both traditional and cutting-edge hematology laboratory technology this book emphasizes international recommendations for testing practices. Illustrative case studies on how technology can be used in patient diagnosis are included. Laboratory Hematology Practice is an invaluable resource for all those working in the field.
Andere Kunden interessierten sich auch für
- Mike LeachPractical Flow Cytometry in Haematology Diagnosis174,99 €
- Hernani CualingNon-Neoplastic Hematopathology and Infections237,99 €
- Alternatives to Blood Transfusion in Transfusion Medicine218,99 €
- Harvey G. KleinMollison's Blood Transfusion in Clinical Medicine199,99 €
- Current and Future Issues in Hemophilia Care110,99 €
- Tissue and Cell Donation152,99 €
- Petra SeeberBasics of Blood Management121,99 €
-
-
-
Expertly edited and endorsed by the International Society for Laboratory Hematology, this is the newest international textbook on all aspects of laboratory hematology. Covering both traditional and cutting-edge hematology laboratory technology this book emphasizes international recommendations for testing practices. Illustrative case studies on how technology can be used in patient diagnosis are included. Laboratory Hematology Practice is an invaluable resource for all those working in the field.
Produktdetails
- Produktdetails
- Verlag: Wiley & Sons / Wiley-Blackwell
- Artikelnr. des Verlages: 1A405162180
- 1. Auflage
- Seitenzahl: 776
- Erscheinungstermin: 7. Mai 2012
- Englisch
- Abmessung: 286mm x 221mm x 46mm
- Gewicht: 2107g
- ISBN-13: 9781405162180
- ISBN-10: 140516218X
- Artikelnr.: 35046588
- Verlag: Wiley & Sons / Wiley-Blackwell
- Artikelnr. des Verlages: 1A405162180
- 1. Auflage
- Seitenzahl: 776
- Erscheinungstermin: 7. Mai 2012
- Englisch
- Abmessung: 286mm x 221mm x 46mm
- Gewicht: 2107g
- ISBN-13: 9781405162180
- ISBN-10: 140516218X
- Artikelnr.: 35046588
Dr Kandice Kottke-Marchant, MD PhD, Section Head, Hemostasis and Thrombosis, Department of Clinical Pathology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA and President, International Society of Laboratory Hematology. She is also a Professor of Pathology at the Cleveland Clinic Lerner College of Medicine and an Adjunct Professor of Biomedical Engineering at Case Western Reserve University. She has published over 100 peer-reviewed publications in the field of haemostasis, is an international expert on platelet testing and aspirin resistance, and has served on review panels from the National Institutes of Health (NIH), College of American Pathologists (CAP), ISO/TC212 and North American Specialized Coagulation Laboratory Association (NASCOLA). She has been a driving force to increase the international visibility and impact of the ISLH. She has been responsible for running the ISLH annual Symposia since 2002. Due to her involvement in haemostasis and the ISLH, Dr. Kottke-Marchant will be uniquely positioned to serve as one of the co-Editors of the Textbook of Laboratory Hematology. Elkin Simson, MD, PCAP, FACSP is the Medical Director of the Center for Clinical Laboratories and Hematology Laboratory at the Mount Sinai Hospital. He is also Associate Professor and Vice Chairman of the Department of Pathology at the Mount Sinai School of Medicine, New York, NY, USA. Dr. Simson was formerly the Vice-President for Medical and Scientific Affairs at Technicon Instruments Corporation, where he participated in the development of the first automated haematology analyzers to combine the CBC and WBC differential into a single instrument. Dr Simson is the Past President of the ISLH and is Vice-President of the International Council for Standardization in Hematology (ICSH). He has been Chairman of the Hematology Area Committee of NCCLS (now CLSI), a member of Council of the National Reference System for the Clinical Laboratory (NRSCL) and the Hematology and Quality Improvement Subcommittees of the NCCCLS. He was a member of the Hematology and Pathology Advisory Panel of the Food and Drug Administration (FDA). Due to his long-time involvement in haematology automation and standards organizations, Dr. Simson is an idea co-editor. The proposed section editors are chosen from international experts in their respective fields; most have also been long-time ISLH members who have been faculty at one or more ISLH Symposia and who have been repeatedly recognized as outstanding speakers and contributors by the participants. Dr Bruce Davis is one of the co-founders of the ISLH and has a long history of involvement in developing automated cellular and flow cytometric technologies. Professor Alberto Orfao from Spain is one of the world's foremost experts on flow cytometry. Professor Samuel Machin is currently President of the British Society of Haematology and is an international authority on haemostasis testing. Stefanie McFadden is a medical technologist who is sought after as a consultant for laboratory management and informatics issues.
Contributors
viii Preface
xiii Abbreviations
xv I Cellular Analysis
1 1 Historical Perspective on Cellular Analysis
3 Elkin Simson 2 Cellular Morphologic Analysis of Peripheral Blood
10 Powers Peterson
Sheila McNeill
and Gene Gulati 3 Automated Cell Analysis: Principles
26 Bruce H. Davis and Patrick W. Barnes 4 Differential Leukocyte Analysis
33 Marie-Christine Béné and Francis Lacombe 5 Automated Platelet Analysis
48 Carol Briggs and Samuel J. Machin 6 Method Standardization in Cellular Analysis
59 Ian Giles & Richard Kendall 7 Spurious counts and spurious results on hematology analyzers: platelets
66 Marc Zandecki
Franck Genevieve
Jérémie Gérard
and Alban Godon 8 Spurious Counts and Spurious Results on Hematology Analyzers: White Blood Cells
Red Blood Cells
Hemoglobin
Red Cell Indices
and Reticulocytes
79 Marc Zandecki
Franck Genevieve
Jérémie Gérard
and Alban Godon 9 Evaluation of Hematology Analyzers
96 Carol Briggs II Flow Cytometry in Hematologic Diagnosis
103 10 Flow Cytometric Specimen Collection
Processing
and Reporting
105 Maryalice Stetler-Stevenson
Bruce Greig
Constance Yuan 11 Validation and Quality Control in Clinical Flow Cytometry
115 Norman B. Purvis and Teri Oldaker 12 A New Paradigm for Cytometric Analysis
131 C. Bruce Bagwell III Molecular Diagnostics
143 13 Sample Collection
Processing
and Storage for Molecular Genetic Testing
145 Bobby L. Boyanton Jr. and Domnita Crisan 14 Development of Amplification-Based Molecular Genetic Testing in Hematology
155 Raymond R. Tubbs 15 Single Nucleotide Polymorphisms in Molecular Diagnostics
168 Gurunathan Murugesan
Seongsoo Jang
and Jin-Yeong Han 16 Molecular Cytogenetic (FISH) Analysis of Hematolymphoid Disorders
181 Mark A. Micale and Anwar N. Mohamed 17 Immunoglobulin and T-Cell Receptor Gene Rearrangement Analysis for Diagnosis of Hematologic Malignancies
199 Jacques J. M. van Dongen
Anton W. Langerak
and Tomasz Szczepan ski 18 Minimal Residual Disease Detection in Acute Myeloid Leukemia by RQ-PCR and Multiparameter Flow Cytometry
220 Wolfgang Kern and Susanne Schnittger 19 Engraftment Analysis using Short Tandem Repeats following Allogeneic Hematopoietic Cell Transplantation
234 Ilka Warshawsky and Hyun-Sook Chi 20 Molecular Profiling Methods in the Diagnosis of Hematologic Disorders
244 Annette S. Kim
Stephen R. Master
and Cherie H. Dunphy 21 The Role of Classical Cytogenetics in Hematologic Diagnosis
267 Kathleen Richkind IV Bone Marrow Analysis
279 22 Bone Marrow Processing and Normal Morphology
281 Karl S. Theil 23 Cytochemical
Immunocytochemical
Histochemical
and Immunohistochemical Staining of Bone Marrow and Peripheral Blood
300 Alexandra Rice and Barbara J. Bain 24 The Myeloproliferative Neoplasms
315 Sindhu Cherian and Brent L. Wood 25 Myelodysplastic Disorders
331 Maryalice Stetler-Stevenson
Joseph A. DiGiuseppe
and Diane C. Arthur 26 Acute Leukemias
345 Joseph A. DiGiuseppe and Laila Mnayer 27 Lymphoproliferative Disorders
364 Robert W. Allan
Samer Z. Al-Quran
Ying Li
and Raul C. Braylan 28 Plasma Cell Disorders
381 Bill G. Richendollar and James R. Cook 29 Diagnosis of Adult Mastocytosis: Role for Bone Marrow Analysis
388 Luis Escribano
Andrés Garcia-Montero
Laura Sanchez-Muñoz
Cristina Teodosio
Ivan Alvarez-Twose
Maria Jara-Acevedo
José Mario Morgado
Julia Almeida
Alberto Orfao for the Spanish Network on Mastocytosis (REMA) 30 Paroxysmal Nocturnal Hemoglobinuria (PNH) Analysis
399 Stephen J. Richards V Hemostasis and Thrombosis
407 31 Sample Collection and Processing in Hemostasis
409 Dorothy M. Adcock 32 Performance and Interpretation of Routine Coagulation Assays
420 Kandice Kottke-Marchant 33 Clotting Factors and Inhibitors: Assays and Interpretation
435 Piet Meijer
H. W. Verbruggen
and Michael Spannagl 34 Diagnosis of von Willebrand Disease
447 Emmanuel J. Favaloro and Jerry Koutts 35 Diagnosis of Fibrinolytic Disorders
460 Wayne Chandler 36 Laboratory Evaluation of Acquired Coagulation Disorders
468 Richard A. Marlar and Katerine Seywerd 37 Platelet Assays and Platelet Dysfunction
480 Paul Harrison and David Keeling 38 Thrombophilia: Assays and Interpretation
492 Sophia Yohe and John Olson 39 Lupus Anticoagulants
Antiphospholipid Antibodies
and Antiphospholipid Syndrome
509 William L. Nichols
Kandice Kottke-Marchant
Marlies R. Ledford-Kraemer
Henry A. Homburger
Layna K. Cardel 40 Heparin-Induced Thrombocytopenia
526 Sixten Selleng and Andreas Greinacher 41 Anticoagulant
Antiplatelet
and Thrombolytic Drugs
535 Laura Green and Samuel J. Machin 42 Guidelines for Evaluation of Coagulation Analyzers and Coagulation Testing
543 Chris Gardiner VI Special Hematology Techniques
553 43 Essentials of Immunohematology
555 A. Bradley Eisenbrey 44 Analysis of Hemoglobinopathies
Hemoglobin Variants and Thalassemias
562 Monica V. E. Gallivan and Piero C. Giordano 45 Nutritional Anemia
586 Ralph Green 46 Hemolytic Anemias Associated with Disorders of Erythrocyte Membrane and Cytoskeleton Proteins
602 May-Jean King
Lesley J. Bruce
Didier Dhermy 47 Body Fluid Analysis
615 David J. Blomberg
Katherine Galagan
and Eric F. Glassy 48 Malaria Analysis
626 Qigui Li
Peter J. Weina
and R. Scott Miller 49 Erythrocyte Sedimentation Rate (ESR)
638 Josep M. Jou VII Point-of-Care Testing
647 50 Needs Analysis and Selection of Point-of-Care Testing Analyzers
649 Albert Huisman 51 Point-of-Care Testing in Hemostasis
655 Steve Kitchen and Dianne Kitchen 52 Point-of-Care Hematology Assays
668 Albert Huisman VIII Management of Information 673 53 Laboratory Management
675 Stefanie L. McFadden and Linda M. Sandhaus 54 Hematology Quality Practices 686 George S. Cembrowski 55 Digital Imaging in Hematology
707 Danny Hsu and Szu-Hee Lee Index
719
viii Preface
xiii Abbreviations
xv I Cellular Analysis
1 1 Historical Perspective on Cellular Analysis
3 Elkin Simson 2 Cellular Morphologic Analysis of Peripheral Blood
10 Powers Peterson
Sheila McNeill
and Gene Gulati 3 Automated Cell Analysis: Principles
26 Bruce H. Davis and Patrick W. Barnes 4 Differential Leukocyte Analysis
33 Marie-Christine Béné and Francis Lacombe 5 Automated Platelet Analysis
48 Carol Briggs and Samuel J. Machin 6 Method Standardization in Cellular Analysis
59 Ian Giles & Richard Kendall 7 Spurious counts and spurious results on hematology analyzers: platelets
66 Marc Zandecki
Franck Genevieve
Jérémie Gérard
and Alban Godon 8 Spurious Counts and Spurious Results on Hematology Analyzers: White Blood Cells
Red Blood Cells
Hemoglobin
Red Cell Indices
and Reticulocytes
79 Marc Zandecki
Franck Genevieve
Jérémie Gérard
and Alban Godon 9 Evaluation of Hematology Analyzers
96 Carol Briggs II Flow Cytometry in Hematologic Diagnosis
103 10 Flow Cytometric Specimen Collection
Processing
and Reporting
105 Maryalice Stetler-Stevenson
Bruce Greig
Constance Yuan 11 Validation and Quality Control in Clinical Flow Cytometry
115 Norman B. Purvis and Teri Oldaker 12 A New Paradigm for Cytometric Analysis
131 C. Bruce Bagwell III Molecular Diagnostics
143 13 Sample Collection
Processing
and Storage for Molecular Genetic Testing
145 Bobby L. Boyanton Jr. and Domnita Crisan 14 Development of Amplification-Based Molecular Genetic Testing in Hematology
155 Raymond R. Tubbs 15 Single Nucleotide Polymorphisms in Molecular Diagnostics
168 Gurunathan Murugesan
Seongsoo Jang
and Jin-Yeong Han 16 Molecular Cytogenetic (FISH) Analysis of Hematolymphoid Disorders
181 Mark A. Micale and Anwar N. Mohamed 17 Immunoglobulin and T-Cell Receptor Gene Rearrangement Analysis for Diagnosis of Hematologic Malignancies
199 Jacques J. M. van Dongen
Anton W. Langerak
and Tomasz Szczepan ski 18 Minimal Residual Disease Detection in Acute Myeloid Leukemia by RQ-PCR and Multiparameter Flow Cytometry
220 Wolfgang Kern and Susanne Schnittger 19 Engraftment Analysis using Short Tandem Repeats following Allogeneic Hematopoietic Cell Transplantation
234 Ilka Warshawsky and Hyun-Sook Chi 20 Molecular Profiling Methods in the Diagnosis of Hematologic Disorders
244 Annette S. Kim
Stephen R. Master
and Cherie H. Dunphy 21 The Role of Classical Cytogenetics in Hematologic Diagnosis
267 Kathleen Richkind IV Bone Marrow Analysis
279 22 Bone Marrow Processing and Normal Morphology
281 Karl S. Theil 23 Cytochemical
Immunocytochemical
Histochemical
and Immunohistochemical Staining of Bone Marrow and Peripheral Blood
300 Alexandra Rice and Barbara J. Bain 24 The Myeloproliferative Neoplasms
315 Sindhu Cherian and Brent L. Wood 25 Myelodysplastic Disorders
331 Maryalice Stetler-Stevenson
Joseph A. DiGiuseppe
and Diane C. Arthur 26 Acute Leukemias
345 Joseph A. DiGiuseppe and Laila Mnayer 27 Lymphoproliferative Disorders
364 Robert W. Allan
Samer Z. Al-Quran
Ying Li
and Raul C. Braylan 28 Plasma Cell Disorders
381 Bill G. Richendollar and James R. Cook 29 Diagnosis of Adult Mastocytosis: Role for Bone Marrow Analysis
388 Luis Escribano
Andrés Garcia-Montero
Laura Sanchez-Muñoz
Cristina Teodosio
Ivan Alvarez-Twose
Maria Jara-Acevedo
José Mario Morgado
Julia Almeida
Alberto Orfao for the Spanish Network on Mastocytosis (REMA) 30 Paroxysmal Nocturnal Hemoglobinuria (PNH) Analysis
399 Stephen J. Richards V Hemostasis and Thrombosis
407 31 Sample Collection and Processing in Hemostasis
409 Dorothy M. Adcock 32 Performance and Interpretation of Routine Coagulation Assays
420 Kandice Kottke-Marchant 33 Clotting Factors and Inhibitors: Assays and Interpretation
435 Piet Meijer
H. W. Verbruggen
and Michael Spannagl 34 Diagnosis of von Willebrand Disease
447 Emmanuel J. Favaloro and Jerry Koutts 35 Diagnosis of Fibrinolytic Disorders
460 Wayne Chandler 36 Laboratory Evaluation of Acquired Coagulation Disorders
468 Richard A. Marlar and Katerine Seywerd 37 Platelet Assays and Platelet Dysfunction
480 Paul Harrison and David Keeling 38 Thrombophilia: Assays and Interpretation
492 Sophia Yohe and John Olson 39 Lupus Anticoagulants
Antiphospholipid Antibodies
and Antiphospholipid Syndrome
509 William L. Nichols
Kandice Kottke-Marchant
Marlies R. Ledford-Kraemer
Henry A. Homburger
Layna K. Cardel 40 Heparin-Induced Thrombocytopenia
526 Sixten Selleng and Andreas Greinacher 41 Anticoagulant
Antiplatelet
and Thrombolytic Drugs
535 Laura Green and Samuel J. Machin 42 Guidelines for Evaluation of Coagulation Analyzers and Coagulation Testing
543 Chris Gardiner VI Special Hematology Techniques
553 43 Essentials of Immunohematology
555 A. Bradley Eisenbrey 44 Analysis of Hemoglobinopathies
Hemoglobin Variants and Thalassemias
562 Monica V. E. Gallivan and Piero C. Giordano 45 Nutritional Anemia
586 Ralph Green 46 Hemolytic Anemias Associated with Disorders of Erythrocyte Membrane and Cytoskeleton Proteins
602 May-Jean King
Lesley J. Bruce
Didier Dhermy 47 Body Fluid Analysis
615 David J. Blomberg
Katherine Galagan
and Eric F. Glassy 48 Malaria Analysis
626 Qigui Li
Peter J. Weina
and R. Scott Miller 49 Erythrocyte Sedimentation Rate (ESR)
638 Josep M. Jou VII Point-of-Care Testing
647 50 Needs Analysis and Selection of Point-of-Care Testing Analyzers
649 Albert Huisman 51 Point-of-Care Testing in Hemostasis
655 Steve Kitchen and Dianne Kitchen 52 Point-of-Care Hematology Assays
668 Albert Huisman VIII Management of Information 673 53 Laboratory Management
675 Stefanie L. McFadden and Linda M. Sandhaus 54 Hematology Quality Practices 686 George S. Cembrowski 55 Digital Imaging in Hematology
707 Danny Hsu and Szu-Hee Lee Index
719
Contributors
viii Preface
xiii Abbreviations
xv I Cellular Analysis
1 1 Historical Perspective on Cellular Analysis
3 Elkin Simson 2 Cellular Morphologic Analysis of Peripheral Blood
10 Powers Peterson
Sheila McNeill
and Gene Gulati 3 Automated Cell Analysis: Principles
26 Bruce H. Davis and Patrick W. Barnes 4 Differential Leukocyte Analysis
33 Marie-Christine Béné and Francis Lacombe 5 Automated Platelet Analysis
48 Carol Briggs and Samuel J. Machin 6 Method Standardization in Cellular Analysis
59 Ian Giles & Richard Kendall 7 Spurious counts and spurious results on hematology analyzers: platelets
66 Marc Zandecki
Franck Genevieve
Jérémie Gérard
and Alban Godon 8 Spurious Counts and Spurious Results on Hematology Analyzers: White Blood Cells
Red Blood Cells
Hemoglobin
Red Cell Indices
and Reticulocytes
79 Marc Zandecki
Franck Genevieve
Jérémie Gérard
and Alban Godon 9 Evaluation of Hematology Analyzers
96 Carol Briggs II Flow Cytometry in Hematologic Diagnosis
103 10 Flow Cytometric Specimen Collection
Processing
and Reporting
105 Maryalice Stetler-Stevenson
Bruce Greig
Constance Yuan 11 Validation and Quality Control in Clinical Flow Cytometry
115 Norman B. Purvis and Teri Oldaker 12 A New Paradigm for Cytometric Analysis
131 C. Bruce Bagwell III Molecular Diagnostics
143 13 Sample Collection
Processing
and Storage for Molecular Genetic Testing
145 Bobby L. Boyanton Jr. and Domnita Crisan 14 Development of Amplification-Based Molecular Genetic Testing in Hematology
155 Raymond R. Tubbs 15 Single Nucleotide Polymorphisms in Molecular Diagnostics
168 Gurunathan Murugesan
Seongsoo Jang
and Jin-Yeong Han 16 Molecular Cytogenetic (FISH) Analysis of Hematolymphoid Disorders
181 Mark A. Micale and Anwar N. Mohamed 17 Immunoglobulin and T-Cell Receptor Gene Rearrangement Analysis for Diagnosis of Hematologic Malignancies
199 Jacques J. M. van Dongen
Anton W. Langerak
and Tomasz Szczepan ski 18 Minimal Residual Disease Detection in Acute Myeloid Leukemia by RQ-PCR and Multiparameter Flow Cytometry
220 Wolfgang Kern and Susanne Schnittger 19 Engraftment Analysis using Short Tandem Repeats following Allogeneic Hematopoietic Cell Transplantation
234 Ilka Warshawsky and Hyun-Sook Chi 20 Molecular Profiling Methods in the Diagnosis of Hematologic Disorders
244 Annette S. Kim
Stephen R. Master
and Cherie H. Dunphy 21 The Role of Classical Cytogenetics in Hematologic Diagnosis
267 Kathleen Richkind IV Bone Marrow Analysis
279 22 Bone Marrow Processing and Normal Morphology
281 Karl S. Theil 23 Cytochemical
Immunocytochemical
Histochemical
and Immunohistochemical Staining of Bone Marrow and Peripheral Blood
300 Alexandra Rice and Barbara J. Bain 24 The Myeloproliferative Neoplasms
315 Sindhu Cherian and Brent L. Wood 25 Myelodysplastic Disorders
331 Maryalice Stetler-Stevenson
Joseph A. DiGiuseppe
and Diane C. Arthur 26 Acute Leukemias
345 Joseph A. DiGiuseppe and Laila Mnayer 27 Lymphoproliferative Disorders
364 Robert W. Allan
Samer Z. Al-Quran
Ying Li
and Raul C. Braylan 28 Plasma Cell Disorders
381 Bill G. Richendollar and James R. Cook 29 Diagnosis of Adult Mastocytosis: Role for Bone Marrow Analysis
388 Luis Escribano
Andrés Garcia-Montero
Laura Sanchez-Muñoz
Cristina Teodosio
Ivan Alvarez-Twose
Maria Jara-Acevedo
José Mario Morgado
Julia Almeida
Alberto Orfao for the Spanish Network on Mastocytosis (REMA) 30 Paroxysmal Nocturnal Hemoglobinuria (PNH) Analysis
399 Stephen J. Richards V Hemostasis and Thrombosis
407 31 Sample Collection and Processing in Hemostasis
409 Dorothy M. Adcock 32 Performance and Interpretation of Routine Coagulation Assays
420 Kandice Kottke-Marchant 33 Clotting Factors and Inhibitors: Assays and Interpretation
435 Piet Meijer
H. W. Verbruggen
and Michael Spannagl 34 Diagnosis of von Willebrand Disease
447 Emmanuel J. Favaloro and Jerry Koutts 35 Diagnosis of Fibrinolytic Disorders
460 Wayne Chandler 36 Laboratory Evaluation of Acquired Coagulation Disorders
468 Richard A. Marlar and Katerine Seywerd 37 Platelet Assays and Platelet Dysfunction
480 Paul Harrison and David Keeling 38 Thrombophilia: Assays and Interpretation
492 Sophia Yohe and John Olson 39 Lupus Anticoagulants
Antiphospholipid Antibodies
and Antiphospholipid Syndrome
509 William L. Nichols
Kandice Kottke-Marchant
Marlies R. Ledford-Kraemer
Henry A. Homburger
Layna K. Cardel 40 Heparin-Induced Thrombocytopenia
526 Sixten Selleng and Andreas Greinacher 41 Anticoagulant
Antiplatelet
and Thrombolytic Drugs
535 Laura Green and Samuel J. Machin 42 Guidelines for Evaluation of Coagulation Analyzers and Coagulation Testing
543 Chris Gardiner VI Special Hematology Techniques
553 43 Essentials of Immunohematology
555 A. Bradley Eisenbrey 44 Analysis of Hemoglobinopathies
Hemoglobin Variants and Thalassemias
562 Monica V. E. Gallivan and Piero C. Giordano 45 Nutritional Anemia
586 Ralph Green 46 Hemolytic Anemias Associated with Disorders of Erythrocyte Membrane and Cytoskeleton Proteins
602 May-Jean King
Lesley J. Bruce
Didier Dhermy 47 Body Fluid Analysis
615 David J. Blomberg
Katherine Galagan
and Eric F. Glassy 48 Malaria Analysis
626 Qigui Li
Peter J. Weina
and R. Scott Miller 49 Erythrocyte Sedimentation Rate (ESR)
638 Josep M. Jou VII Point-of-Care Testing
647 50 Needs Analysis and Selection of Point-of-Care Testing Analyzers
649 Albert Huisman 51 Point-of-Care Testing in Hemostasis
655 Steve Kitchen and Dianne Kitchen 52 Point-of-Care Hematology Assays
668 Albert Huisman VIII Management of Information 673 53 Laboratory Management
675 Stefanie L. McFadden and Linda M. Sandhaus 54 Hematology Quality Practices 686 George S. Cembrowski 55 Digital Imaging in Hematology
707 Danny Hsu and Szu-Hee Lee Index
719
viii Preface
xiii Abbreviations
xv I Cellular Analysis
1 1 Historical Perspective on Cellular Analysis
3 Elkin Simson 2 Cellular Morphologic Analysis of Peripheral Blood
10 Powers Peterson
Sheila McNeill
and Gene Gulati 3 Automated Cell Analysis: Principles
26 Bruce H. Davis and Patrick W. Barnes 4 Differential Leukocyte Analysis
33 Marie-Christine Béné and Francis Lacombe 5 Automated Platelet Analysis
48 Carol Briggs and Samuel J. Machin 6 Method Standardization in Cellular Analysis
59 Ian Giles & Richard Kendall 7 Spurious counts and spurious results on hematology analyzers: platelets
66 Marc Zandecki
Franck Genevieve
Jérémie Gérard
and Alban Godon 8 Spurious Counts and Spurious Results on Hematology Analyzers: White Blood Cells
Red Blood Cells
Hemoglobin
Red Cell Indices
and Reticulocytes
79 Marc Zandecki
Franck Genevieve
Jérémie Gérard
and Alban Godon 9 Evaluation of Hematology Analyzers
96 Carol Briggs II Flow Cytometry in Hematologic Diagnosis
103 10 Flow Cytometric Specimen Collection
Processing
and Reporting
105 Maryalice Stetler-Stevenson
Bruce Greig
Constance Yuan 11 Validation and Quality Control in Clinical Flow Cytometry
115 Norman B. Purvis and Teri Oldaker 12 A New Paradigm for Cytometric Analysis
131 C. Bruce Bagwell III Molecular Diagnostics
143 13 Sample Collection
Processing
and Storage for Molecular Genetic Testing
145 Bobby L. Boyanton Jr. and Domnita Crisan 14 Development of Amplification-Based Molecular Genetic Testing in Hematology
155 Raymond R. Tubbs 15 Single Nucleotide Polymorphisms in Molecular Diagnostics
168 Gurunathan Murugesan
Seongsoo Jang
and Jin-Yeong Han 16 Molecular Cytogenetic (FISH) Analysis of Hematolymphoid Disorders
181 Mark A. Micale and Anwar N. Mohamed 17 Immunoglobulin and T-Cell Receptor Gene Rearrangement Analysis for Diagnosis of Hematologic Malignancies
199 Jacques J. M. van Dongen
Anton W. Langerak
and Tomasz Szczepan ski 18 Minimal Residual Disease Detection in Acute Myeloid Leukemia by RQ-PCR and Multiparameter Flow Cytometry
220 Wolfgang Kern and Susanne Schnittger 19 Engraftment Analysis using Short Tandem Repeats following Allogeneic Hematopoietic Cell Transplantation
234 Ilka Warshawsky and Hyun-Sook Chi 20 Molecular Profiling Methods in the Diagnosis of Hematologic Disorders
244 Annette S. Kim
Stephen R. Master
and Cherie H. Dunphy 21 The Role of Classical Cytogenetics in Hematologic Diagnosis
267 Kathleen Richkind IV Bone Marrow Analysis
279 22 Bone Marrow Processing and Normal Morphology
281 Karl S. Theil 23 Cytochemical
Immunocytochemical
Histochemical
and Immunohistochemical Staining of Bone Marrow and Peripheral Blood
300 Alexandra Rice and Barbara J. Bain 24 The Myeloproliferative Neoplasms
315 Sindhu Cherian and Brent L. Wood 25 Myelodysplastic Disorders
331 Maryalice Stetler-Stevenson
Joseph A. DiGiuseppe
and Diane C. Arthur 26 Acute Leukemias
345 Joseph A. DiGiuseppe and Laila Mnayer 27 Lymphoproliferative Disorders
364 Robert W. Allan
Samer Z. Al-Quran
Ying Li
and Raul C. Braylan 28 Plasma Cell Disorders
381 Bill G. Richendollar and James R. Cook 29 Diagnosis of Adult Mastocytosis: Role for Bone Marrow Analysis
388 Luis Escribano
Andrés Garcia-Montero
Laura Sanchez-Muñoz
Cristina Teodosio
Ivan Alvarez-Twose
Maria Jara-Acevedo
José Mario Morgado
Julia Almeida
Alberto Orfao for the Spanish Network on Mastocytosis (REMA) 30 Paroxysmal Nocturnal Hemoglobinuria (PNH) Analysis
399 Stephen J. Richards V Hemostasis and Thrombosis
407 31 Sample Collection and Processing in Hemostasis
409 Dorothy M. Adcock 32 Performance and Interpretation of Routine Coagulation Assays
420 Kandice Kottke-Marchant 33 Clotting Factors and Inhibitors: Assays and Interpretation
435 Piet Meijer
H. W. Verbruggen
and Michael Spannagl 34 Diagnosis of von Willebrand Disease
447 Emmanuel J. Favaloro and Jerry Koutts 35 Diagnosis of Fibrinolytic Disorders
460 Wayne Chandler 36 Laboratory Evaluation of Acquired Coagulation Disorders
468 Richard A. Marlar and Katerine Seywerd 37 Platelet Assays and Platelet Dysfunction
480 Paul Harrison and David Keeling 38 Thrombophilia: Assays and Interpretation
492 Sophia Yohe and John Olson 39 Lupus Anticoagulants
Antiphospholipid Antibodies
and Antiphospholipid Syndrome
509 William L. Nichols
Kandice Kottke-Marchant
Marlies R. Ledford-Kraemer
Henry A. Homburger
Layna K. Cardel 40 Heparin-Induced Thrombocytopenia
526 Sixten Selleng and Andreas Greinacher 41 Anticoagulant
Antiplatelet
and Thrombolytic Drugs
535 Laura Green and Samuel J. Machin 42 Guidelines for Evaluation of Coagulation Analyzers and Coagulation Testing
543 Chris Gardiner VI Special Hematology Techniques
553 43 Essentials of Immunohematology
555 A. Bradley Eisenbrey 44 Analysis of Hemoglobinopathies
Hemoglobin Variants and Thalassemias
562 Monica V. E. Gallivan and Piero C. Giordano 45 Nutritional Anemia
586 Ralph Green 46 Hemolytic Anemias Associated with Disorders of Erythrocyte Membrane and Cytoskeleton Proteins
602 May-Jean King
Lesley J. Bruce
Didier Dhermy 47 Body Fluid Analysis
615 David J. Blomberg
Katherine Galagan
and Eric F. Glassy 48 Malaria Analysis
626 Qigui Li
Peter J. Weina
and R. Scott Miller 49 Erythrocyte Sedimentation Rate (ESR)
638 Josep M. Jou VII Point-of-Care Testing
647 50 Needs Analysis and Selection of Point-of-Care Testing Analyzers
649 Albert Huisman 51 Point-of-Care Testing in Hemostasis
655 Steve Kitchen and Dianne Kitchen 52 Point-of-Care Hematology Assays
668 Albert Huisman VIII Management of Information 673 53 Laboratory Management
675 Stefanie L. McFadden and Linda M. Sandhaus 54 Hematology Quality Practices 686 George S. Cembrowski 55 Digital Imaging in Hematology
707 Danny Hsu and Szu-Hee Lee Index
719