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Malaria and soil-transmitted helminths are co-endemic and have major public health significance. This research study was aimed to ascertain the people's knowledge, attitudes, and perception about malaria and soil-transmitted helminths in Ndeama village in Ulakwo autonomous community, Owerri North Local Government Area between the month of February and August 2017. Therefore, this study highlights a critical need for targeting health messages towards poorly educated rural dwellers in order to empower them with the knowledge and resources to recognize and manage their health problems.