This book introduces fundamental concepts and builds upon these using topical and relevant historical examples. Its improved format includes learning objectives and summaries of each chapter, as well as questions and answers suitable for self-assessment.
This book introduces fundamental concepts and builds upon these using topical and relevant historical examples. Its improved format includes learning objectives and summaries of each chapter, as well as questions and answers suitable for self-assessment.
John Timbrell is Emeritus Professor of Biochemical Toxicology in the Pharmacy Department at King's College London and was a member of the Commitee on Toxicigy, U.K.Govenment. He was the founding Editor of the journal Biomarkers (Taylor and Francis Ltd). Publishers. He has been involved with the teaching and development of toxicology courses at both undergraduate and postgraduate level for 30 years. Frank A. Barile is retired Professor of Toxicology in the Pharmaceutical sciences Department, St. John's University College of Pharmacy and Health Sciences, New York. He is past President of the In Vitro and Alternative Methods (IVAM) Specialty Section of the U.S. Society of Toxicology and a former member of the Scientific Advisory Committee for Alternative Toxicological Methods (SACATM), NIEHS, U.S. National Institutes of Health. He is former Chief Editor of Toxicology in Vitro.
Inhaltsangabe
1. Introduction. 2. Dose-Response Relationship. 3. Exposure-Response Relationship. 4. Disposition of Toxic Compounds. 5. Metabolism of Xenobiotic Compounds. 6. Target Organ Toxicity. 7. Carcinogenic and Mutagenic Compounds. 8. Drugs as Toxic Substances. 9. Industry Toxicology. 10. Food Additives and Contaminants. 11. Pesticides and Herbicides. 12. Environmental Pollutants. 13. Natural Products. 14. Commercial and Domestic Products. 15. Fundamentals of Toxicity Testing. 16. Risk Assessment. 17. Antidotes and Treatment of Poisoning. Answers to Chapter Questions. Glossary.
