Intratumor Diversity and Clonal Evolution in Cancer

Volume 112
Herausgegeben:Gisselsson, David

• Gebundenes Buch

Produktbeschreibung

This specialized volume of Advances in Cancer Research is dedicated to the complex and largely unexplored field of intratumor diversity, with respect to differences in both genotype and phenotype among cell populations within tumors.

Produktdetails

• Advances in Cancer Research Volume 112
• Verlag: Academic Press / Elsevier Science & Technology
• Artikelnr. des Verlages: C2010-0-66716-2
• Seitenzahl: 368
• Erscheinungstermin: 29. September 2011
• Englisch
• Abmessung: 21mm x 152mm x 229mm
• Gewicht: 708g
• ISBN-13: 9780123876881
• ISBN-10: 0123876885
• Artikelnr.: 33865348

Inhaltsangabe

1. Introduction



2. Role of telomere dysfunction in genetic intratumour diversity



3. How mitotic errors contribute to karyotypic diversity in cancer



4. Nuclear Remodelling as a Mechanism for Genomic Instability in Cancer



5. Cytogenetic Analysis of Tumor Clonality



6. Genotyping techniques to address diversity in tumors



7. Prostate Cancer as a Model System for Genetic Diversity in Tumours



8. Evolutionary mechanisms and diversity in cancer



9. Cancer stem cells in tumor heterogeneity



10. Cancer: Beyond Speciation