This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management. Head-and-neck cancers are a complex clinical entity and their response to…mehr
This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management. Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks. In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.
After obtaining his degree in Radio-Oncology at the University of Liege, Belgium, Jacques Bernier completed his training at the MD Anderson Cancer Center, Houston, and the Curie Institute, Paris. In 2006 he joined the Swiss Genolier Medical Network, where since then he has been chairing the Radio-Oncology Department. Throughout most of his career, Jacques Bernier has been heavily involved with translational and clinical research. From 2000 to 2006 Jacques Bernier was Chairman of the Head and Neck Group of the EORTC. He currently serves as an Editorial Board member of various international peer-reviewed journals, including ¿Journal of Clinical Oncology¿. He is an Associate Editor of ¿Annals of Oncology¿ (since 2010), and ¿Oral Oncology¿ (since January 2011). A Course Director at the European School of Oncology since 1990, Jacques Bernier is also the Chairman of the International Conference on Translational Research in Radio-Oncology - ICTR, organized every three years in Switzerland. He serves as a regular member of advisory boards for many pharmaceutical companies. He is President of the Foundation for the Advancement of Radiation Oncology ¿ FARO, in Geneva, member of the Executive Board of Euro-Asian Society of Mastology - EURAMA, Board of Trustees of ¿Science for Peace¿ and Scientific Committee of the ¿Umberto Veronesi Foundation¿ in Milan.
Inhaltsangabe
Table of ContentsHead and Neck Cancer: Multimodality Management, 2nd Edition Editors: Jacques Bernier Ch. 1: Epidemiology and Aetiology of Head and Neck CancersNewell W. JohnsonHemantha K. Amarasinghe Ch. 2: Head and Neck Cancer PreventionFausto ChiesaAngelo OstuniRoberto GrigolatoLuca CalabreseMohssen Ansarin Ch. 3: Cellular and Molecular Pathology of Head and Neck TumorsAdel K. El-Naggar Ch. 4: Oncogenomics/Proteomics of Head and Neck CancersJason I. KassHoward S. MoskowitzJennifer R. Grandis Ch. 5: Genetics and Epigenetics of Head and Neck CancerJagtar DhandaRichard J. Shaw Ch. 6: Immunology of Head and Neck CancerBenjamin A. KansySteve C. LeeRobert L. Ferris Ch. 7: Biomarkers in Head and Neck CancerHyunseok KangChristine H. ChungArlene A. Forastiere Ch. 8: HPV and EBV in Head and Neck CancerJeffrey BrumbaughRobert L. FerrisShen Hu Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCCBrian O'SullivanJatin P. ShahWilliam M. Lydiatt Ch. 10: Preclinical Models of Head and Neck Squamous Cell CarcinomaC.L. ZuurA.J.C. DohmenMichiel W. van den BrekelXiao-Jing WangStephen Malkoski Ch. 11: Translational Research in Head and Neck OncologyDavid S. YooDavid M. Brizel Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and TreatmentYungan TaoJean Bourhis Ch. 13: Imaging of Head and Neck CancersTaha S. MerajSuyash MohanGaurang V. Shah Ch. 14: Ultrasound Investigations in Head & Neck Cancer PatientsYolanda Y.P. LeeKa Tak WongKunwar Suryaveer Singh BhatiaAnil Tejbhan Ahuja Ch. 15: Sentinel Node BiopsyOliver J. SmithLee W.T. AlkureishiGary L. Ross Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck CancerMarsha ReyngoldEdward J. ShinNancy Lee Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer PatientsThomas LeroyEric Lartigau Ch. 18: Proton Beam Therapy for Head and Neck CancerDanielle N. MargalitJudy A. AdamsHanne M. KooyAnnie W. ChanCh. 20: Molecular Targeted Therapies in Head and Neck CancerZachary S. MorrisAnne M. TraynorPaul M. Harari Ch. 21: Laser Endoscopic TreatmentPierre MoreauPierre Demez Ch. 22: Transoral robotic surgery in head and neck cancerSylvain Morinière Ch. 23: Multidisciplinary Management of Skull Base and Superstructure TumorsGiulio CantùCarlo L. SoleroStefano RiccioSarah ColomboMadia Pompilio Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancersAlexander D. Rapidis Ch. 25: Oral OncologyRuth Aponte WessonTheresa M. HofstedeRichard C. CardosoPattii MontgomeryAlexander M. WonJack W. MartinMark S. Chambers Ch. 26: Management of Nasopharyngeal CarcinomaWai Tong NgRoger K.C. NganSiu Hong ChanHenry SzeJimmy Y.W. ChanAnne W.M. Lee Ch. 27: Multidisciplinary management of oropharynx carcinomasBeth M. BeadleDavid I. Rosenthal Ch. 28: Multidisciplinary Management of Hypopharyngeal CarcinomaMarc HamoirJean-Pascal MachielsSandra SchmitzVincent Gregoire Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and ManagementCarol M. LewisSteven B. ChinnChris HolsingerRandal S. Weber Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal CancersNabil F. SabaJ. Trad WadsworthJonathan J. BeitlerFadlo R. Khuri Ch. 31: Programs of Organ and Function PreservationJean Louis Lefebvre Ch. 32: Principles and New Approaches in Surgical ReconstructionAndreas DietzMilos FischerChristina MagillBruce H. Haughey Ch. 33: Multidisciplinary treatment of the neckRemco de BreeJohannes A. LangendijkC.R. Leemans Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck CancerAssuntina G. SaccoEzra E. Cohen Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck CancerRicardo HittAna Lopez-MartinJuan J. CruzRobert I. Haddad Ch. 36: Management of Salivary Gland CancerLaura D. LocatiMarco GuzzoEster OrlandiLisa Licitra Ch. 37: Primary Mucosal Melanomas of the Head and NeckJuliette ThariatAnne-Catherine BaglinPierre Yves MarcyCaroline EvenAntoine Moya-PlanaYusuke DemizuAdam S. GardenMarco KrengliMichael A. Postow Ch. 38: Head & Neck Cutaneous MelanomaMina N. LeMichael A. PostowSnehal G. Patel Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary SiteNicholas PavlidisGeorgios Plataniotis Ch. 40: The Management of Thyroid and Parathyroid CancerNasheed M. HossainColleen VeloskiRanee Mehra Ch. 41: Head and Neck ParagangliomasJulian KünzelMichael HainzHeidi RossmannChristoph Matthias Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckPetr SzturzJan B. Vermorken Ch. 43: Phase I study methodology in head and neck oncologyAaron HansenChristophe Le Tourneau Ch. 44: Treatment of the Elderly Head and Neck Cancer PatientJean-Claude HoriotMatti Aapro Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer PatientsAndy TrottiNikhil RaoAvraham EisbruchDavid I. Rosenthal Ch. 46: Advances in Management of Complications for Head and Neck Cancer TherapyBarbara MurphyJie DengMark J. StavasHeidi GanzerJoel B. Epstein Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer PatientsKatherine A. Hutcheson Ch. 48: Salvage Therapy in Head and Neck Cancer PatientsJohn HeaphyRod RezaeePierre Lavertu Ch. 49: Quality of Life in Head and Neck Cancer PatientsJolie Ringash Ch. 50: Psycho-oncologic aspects of head and neck cancer patientsMichel Reich Ch. 51: Advances in Nanomedicine for Head and Neck CancerSajanlal R. PanikkanvalappilMostafa A. El-SayedIvan H. El-Sayed Ch. 52: Head and Neck Quality Assurance 2014Thomas J. FitzGeraldMaryann Bishop-JodoinDavid S. FollowillJames M. GalvinMichael V. KnoppJeff M. MichalskiMark RosenJonathan M. GlanzmanPaul RavaAllison SacherDavid J. GoffAlec VaeziKenneth Ulin
Table of ContentsHead and Neck Cancer: Multimodality Management, 2nd Edition Editors: Jacques Bernier Ch. 1: Epidemiology and Aetiology of Head and Neck CancersNewell W. JohnsonHemantha K. Amarasinghe Ch. 2: Head and Neck Cancer PreventionFausto ChiesaAngelo OstuniRoberto GrigolatoLuca CalabreseMohssen Ansarin Ch. 3: Cellular and Molecular Pathology of Head and Neck TumorsAdel K. El-Naggar Ch. 4: Oncogenomics/Proteomics of Head and Neck CancersJason I. KassHoward S. MoskowitzJennifer R. Grandis Ch. 5: Genetics and Epigenetics of Head and Neck CancerJagtar DhandaRichard J. Shaw Ch. 6: Immunology of Head and Neck CancerBenjamin A. KansySteve C. LeeRobert L. Ferris Ch. 7: Biomarkers in Head and Neck CancerHyunseok KangChristine H. ChungArlene A. Forastiere Ch. 8: HPV and EBV in Head and Neck CancerJeffrey BrumbaughRobert L. FerrisShen Hu Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCCBrian O'SullivanJatin P. ShahWilliam M. Lydiatt Ch. 10: Preclinical Models of Head and Neck Squamous Cell CarcinomaC.L. ZuurA.J.C. DohmenMichiel W. van den BrekelXiao-Jing WangStephen Malkoski Ch. 11: Translational Research in Head and Neck OncologyDavid S. YooDavid M. Brizel Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and TreatmentYungan TaoJean Bourhis Ch. 13: Imaging of Head and Neck CancersTaha S. MerajSuyash MohanGaurang V. Shah Ch. 14: Ultrasound Investigations in Head & Neck Cancer PatientsYolanda Y.P. LeeKa Tak WongKunwar Suryaveer Singh BhatiaAnil Tejbhan Ahuja Ch. 15: Sentinel Node BiopsyOliver J. SmithLee W.T. AlkureishiGary L. Ross Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck CancerMarsha ReyngoldEdward J. ShinNancy Lee Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer PatientsThomas LeroyEric Lartigau Ch. 18: Proton Beam Therapy for Head and Neck CancerDanielle N. MargalitJudy A. AdamsHanne M. KooyAnnie W. ChanCh. 20: Molecular Targeted Therapies in Head and Neck CancerZachary S. MorrisAnne M. TraynorPaul M. Harari Ch. 21: Laser Endoscopic TreatmentPierre MoreauPierre Demez Ch. 22: Transoral robotic surgery in head and neck cancerSylvain Morinière Ch. 23: Multidisciplinary Management of Skull Base and Superstructure TumorsGiulio CantùCarlo L. SoleroStefano RiccioSarah ColomboMadia Pompilio Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancersAlexander D. Rapidis Ch. 25: Oral OncologyRuth Aponte WessonTheresa M. HofstedeRichard C. CardosoPattii MontgomeryAlexander M. WonJack W. MartinMark S. Chambers Ch. 26: Management of Nasopharyngeal CarcinomaWai Tong NgRoger K.C. NganSiu Hong ChanHenry SzeJimmy Y.W. ChanAnne W.M. Lee Ch. 27: Multidisciplinary management of oropharynx carcinomasBeth M. BeadleDavid I. Rosenthal Ch. 28: Multidisciplinary Management of Hypopharyngeal CarcinomaMarc HamoirJean-Pascal MachielsSandra SchmitzVincent Gregoire Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and ManagementCarol M. LewisSteven B. ChinnChris HolsingerRandal S. Weber Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal CancersNabil F. SabaJ. Trad WadsworthJonathan J. BeitlerFadlo R. Khuri Ch. 31: Programs of Organ and Function PreservationJean Louis Lefebvre Ch. 32: Principles and New Approaches in Surgical ReconstructionAndreas DietzMilos FischerChristina MagillBruce H. Haughey Ch. 33: Multidisciplinary treatment of the neckRemco de BreeJohannes A. LangendijkC.R. Leemans Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck CancerAssuntina G. SaccoEzra E. Cohen Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck CancerRicardo HittAna Lopez-MartinJuan J. CruzRobert I. Haddad Ch. 36: Management of Salivary Gland CancerLaura D. LocatiMarco GuzzoEster OrlandiLisa Licitra Ch. 37: Primary Mucosal Melanomas of the Head and NeckJuliette ThariatAnne-Catherine BaglinPierre Yves MarcyCaroline EvenAntoine Moya-PlanaYusuke DemizuAdam S. GardenMarco KrengliMichael A. Postow Ch. 38: Head & Neck Cutaneous MelanomaMina N. LeMichael A. PostowSnehal G. Patel Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary SiteNicholas PavlidisGeorgios Plataniotis Ch. 40: The Management of Thyroid and Parathyroid CancerNasheed M. HossainColleen VeloskiRanee Mehra Ch. 41: Head and Neck ParagangliomasJulian KünzelMichael HainzHeidi RossmannChristoph Matthias Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckPetr SzturzJan B. Vermorken Ch. 43: Phase I study methodology in head and neck oncologyAaron HansenChristophe Le Tourneau Ch. 44: Treatment of the Elderly Head and Neck Cancer PatientJean-Claude HoriotMatti Aapro Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer PatientsAndy TrottiNikhil RaoAvraham EisbruchDavid I. Rosenthal Ch. 46: Advances in Management of Complications for Head and Neck Cancer TherapyBarbara MurphyJie DengMark J. StavasHeidi GanzerJoel B. Epstein Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer PatientsKatherine A. Hutcheson Ch. 48: Salvage Therapy in Head and Neck Cancer PatientsJohn HeaphyRod RezaeePierre Lavertu Ch. 49: Quality of Life in Head and Neck Cancer PatientsJolie Ringash Ch. 50: Psycho-oncologic aspects of head and neck cancer patientsMichel Reich Ch. 51: Advances in Nanomedicine for Head and Neck CancerSajanlal R. PanikkanvalappilMostafa A. El-SayedIvan H. El-Sayed Ch. 52: Head and Neck Quality Assurance 2014Thomas J. FitzGeraldMaryann Bishop-JodoinDavid S. FollowillJames M. GalvinMichael V. KnoppJeff M. MichalskiMark RosenJonathan M. GlanzmanPaul RavaAllison SacherDavid J. GoffAlec VaeziKenneth Ulin
Rezensionen
"This exceptional, up-to-date resource on the basic and clinical science of head and neck cancer synthesizes a vast amount of information in a single, comprehensive resource. ... Specialists ... as well as trainees in these fields, will find this an outstanding resource. ... an extraordinary guide to this field. Those looking for a comprehensive resource on head and neck cancer will not find a better one. ... it will soon become the definitive book on head and neck cancer." (John David Cramer, Doody's Book Reviews, January, 2017)
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