From the Reviews of the First Edition:
"This magnificent book attempts to catalogue and introduce all aspects of modern statistical genetics...I can thoroughly recommend it."
Short Book Reviews of ISI
"...extremely well written and referenced work, which must come highly recommended..."
Statistical Methods in Medical Research
* Provides comprehensive coverage of a thriving area of research
* Features nine newly commissioned chapters
* All existing chapters have been fully updated with new advances in the field and new references
* Now includes a glossary of terms, and a list of acronyms and abbreviations.
* Features extensive cross-referencing between chapters.
* Each chapter is written by a leading international authority from the field.
* Complemented by examples, case studies, and references to useful resources on the web.
"...sure to become the standard reference for students and researchers in all fields of statistical genetics...one of those rare commodities, an edited volume whose intellectual value may actually increase with time..." (Heredity, 2003)
PART I: SEQUENCE, STRUCTURE AND EXPRESSION.
Chromosome Maps.
Statistical Significance in Biological Sequence Comparison.
Bayesian Methods in Genomics.
Statistical Approaches in Eukaryotic Gene Prediction.
Comparative Genomics.
Gene-Expression 1.
Protein Structure.
Probabilistic Models for the Study of Protein Evolution.
PART II: EVOLUTIONARY GENETICS.
Adaptive Molecular Evolution.
Genome Evolution.
Virus Evolution.
Application of the Likelihood Function in Phylogenetic Analysis.
Phylogenetics: Parsimony and Distance Methods.
Evolutionary Quantitative Genetics.
PART III: ANIMAL AND PLANT BREEDING.
QTLs in Inbred Lines.
Mapping Quantitative Trait Loci in Outbred Pedigrees.
Inferences about Breeding Values.
Marker Assisted Selection and Introgression.
PART IV: POPULATION GENETICS.
Mathematical Models in Population Genetics.
Coalescent Theory.
Inference Under the Coalescent.
Linkage Disequilibrium and Recombination.
Inferences from Spatial Population Genetics.
Analysis of Population Subdivision.
Conservation Genetics.
Genetic History of the Human Species.
Forensics.
PART V: GENETIC EPIDEMIOLOGY.
Introduction to Genetic Epidemiology.
Statistical Basis of Risk Calculations: A Status Report.
Linkage Analysis.
Nonparametric Linkage.
Population Association.
The Transmission/Disequilibrium Test.
Pharmacogenetics.
PART VI: APPLICATIONS.
Ethics in the Use of Statistics in Genetics
"This magnificent book attempts to catalogue and introduce all aspects of modern statistical genetics...I can thoroughly recommend it."
Short Book Reviews of ISI
"...extremely well written and referenced work, which must come highly recommended..."
Statistical Methods in Medical Research
* Provides comprehensive coverage of a thriving area of research
* Features nine newly commissioned chapters
* All existing chapters have been fully updated with new advances in the field and new references
* Now includes a glossary of terms, and a list of acronyms and abbreviations.
* Features extensive cross-referencing between chapters.
* Each chapter is written by a leading international authority from the field.
* Complemented by examples, case studies, and references to useful resources on the web.
"...sure to become the standard reference for students and researchers in all fields of statistical genetics...one of those rare commodities, an edited volume whose intellectual value may actually increase with time..." (Heredity, 2003)
PART I: SEQUENCE, STRUCTURE AND EXPRESSION.
Chromosome Maps.
Statistical Significance in Biological Sequence Comparison.
Bayesian Methods in Genomics.
Statistical Approaches in Eukaryotic Gene Prediction.
Comparative Genomics.
Gene-Expression 1.
Protein Structure.
Probabilistic Models for the Study of Protein Evolution.
PART II: EVOLUTIONARY GENETICS.
Adaptive Molecular Evolution.
Genome Evolution.
Virus Evolution.
Application of the Likelihood Function in Phylogenetic Analysis.
Phylogenetics: Parsimony and Distance Methods.
Evolutionary Quantitative Genetics.
PART III: ANIMAL AND PLANT BREEDING.
QTLs in Inbred Lines.
Mapping Quantitative Trait Loci in Outbred Pedigrees.
Inferences about Breeding Values.
Marker Assisted Selection and Introgression.
PART IV: POPULATION GENETICS.
Mathematical Models in Population Genetics.
Coalescent Theory.
Inference Under the Coalescent.
Linkage Disequilibrium and Recombination.
Inferences from Spatial Population Genetics.
Analysis of Population Subdivision.
Conservation Genetics.
Genetic History of the Human Species.
Forensics.
PART V: GENETIC EPIDEMIOLOGY.
Introduction to Genetic Epidemiology.
Statistical Basis of Risk Calculations: A Status Report.
Linkage Analysis.
Nonparametric Linkage.
Population Association.
The Transmission/Disequilibrium Test.
Pharmacogenetics.
PART VI: APPLICATIONS.
Ethics in the Use of Statistics in Genetics