Provides perspective, covers recent developments in technologies that have enabled the expanded use of biomarkers, discusses biomarker characterization and validation, and applications throughout the discovery-development continuum, including Companion Diagnostic ( CDX) development.
Provides perspective, covers recent developments in technologies that have enabled the expanded use of biomarkers, discusses biomarker characterization and validation, and applications throughout the discovery-development continuum, including Companion Diagnostic ( CDX) development.
Introduction. What is a Biomarker and its Role in Drug Development? Biomarkers in Discovery and PreClinical Safety. Translating From Pre-Clinical Results to Clinical and Back. Biomarkers in Clinical Trials -Design Considerations for Biomarker Informed Clinical Trials. The road ahead: Identification of the hurdles and solutions to the implementation of personalized medicine in healthcare. Lessons from the past and pioneers of the future. Paving a new era of personalized medicine: Emerging technologies. The next frontiers of therapeutic target areas: Autoimmunity, inflammation, respiratory, metabolic, cardiovascular and neurological diseases. Lessons Learned: What have we learned and what is the next challenge?
Introduction. What is a Biomarker and its Role in Drug Development? Biomarkers in Discovery and PreClinical Safety. Translating From Pre-Clinical Results to Clinical and Back. Biomarkers in Clinical Trials -Design Considerations for Biomarker Informed Clinical Trials. The road ahead: Identification of the hurdles and solutions to the implementation of personalized medicine in healthcare. Lessons from the past and pioneers of the future. Paving a new era of personalized medicine: Emerging technologies. The next frontiers of therapeutic target areas: Autoimmunity, inflammation, respiratory, metabolic, cardiovascular and neurological diseases. Lessons Learned: What have we learned and what is the next challenge?
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