Handbook of Antimicrobial Resistance

Herausgeber: Berghuis, Albert; Matlashewski, Greg

• Gebundenes Buch

Produktbeschreibung

This is a comprehensive tool covering all manifestations of antimicrobial resistance, with viral, bacterial, parasitical and fungal resistance each given a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.¿

Produktdetails

• Verlag: Springer Nature Singapore / Springer US
• 2017
• Seitenzahl: 606
• Erscheinungstermin: 14. März 2018
• Englisch
• ISBN-13: 9781493906956
• ISBN-10: 149390695X
• Artikelnr.: 40460192

Autorenporträt

Matthias Gotte, Department of Medical Microbiology and Immunology, University of Alberta, Canada Albert M. Berguis, Department of Biochemistry, McGill University, Canada Greg Matlashewski, Department of Microbiology and Immunology, McGill University, Canada Donald Sheppard, Department of Microbiology and Immunology, McGill University, Canada Mark A. Wainberg, Department of Microbiology and Immunology, McGill University, Canada

Inhaltsangabe

Bacteria.
Origins of antibiotic resistance (Resistome).
Dissemination of antibiotic resistance.
Mechanisms of antibiotic resistance.
Strategies for combating antibiotic resistance.
 Multiple
drug
resistant bacteria.
 Resistant Tuberculosis.
MRSA.
 Fungi.
Microevolution of drug resistance.
 Environmental induction of azole resistance in medical molds.
Echinocandin resistance in medically relevant fungi.
Role of drug efflux in azole resistance.
 Parasites.
 Drug
resistant Leishmania.
Drug resistance in Helminth infections.
 Drug resistance in Malaria.
Drug resistance in schistosome infections.
 Drug resistance in trypanosome infections.
 HIV.
 Resistance to RT inhibitors.
 Resistance to Integrase Inhibitors.
 Resistance to Entry inhibitors.
 Resistance Testing.
 Virology.
Resistance to viral protease inhibitors: The substrate envelope.
 Resistance to new Direct
Acting
Antivirals against HCV.
HBV Resistance.
 Resistance to antiherpetic drugs.
Influenza Resistance.