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This issue covers a broad selection of topics critical to psychiatrist and any physician who treats older patients. Topics include: Epidemiology, clinical evaluation, and treatment of dementing disorders, late-life psychosis; suicide in late life; depression in primary care; structural neuroimaging of geriatric depression; gene-environment interactions in geriatric depression; treatment of geriatric depression; etiological Theories of Late-Life depression; geriatric bipolar disorder; psychotherapies in geriatric depression; home-based care of the elderly with mental disorders; functional neuroimaging in geriatric depression; models of treatment engagement of geriatric persons with mental disorders; and mental health service delivery to the elderly.